<br>Part I. Central Nervous System<br><br>Section A. Metabolic Diseases – Hugo W. Moser<br> <br>Chapter 1: Leukodystrophies<br>Chapter 2: Lysosomal Disorders of the Nervous System<br>Chapter 3: The Neurobiology of Peroxisomal Disorders<br>Chapter 4: Creatine Deficiency Syndromes<br><br>Section B. Neurodegenerative Disorders – Gregor Wenning <br><br>Chapter 5: Parkinson’s Disease<br>Chapter 6: Alzheimer Disease<br>Chapter 7: Multiple System Atrophy<br>Chapter 8: Olivopontocerebellar Atrophy (OPCA)<br>Chapter 9: Neurobiology of Progressive Supranuclear Palsy<br><br>Section C. Genetic Diseases – Christopher Gomez <br><br>Chapter 10: Protein Aggregation Disorders<br>Chapter 11: RNA-Based Disorders of Muscle and Brain<br>Chapter 12: Ion Channel Disorders<br>Chapter 13: Spinocerebellar Ataxia Type 1<br>Chapter 14: Shared Transcriptional Consequences of Mitochondrial Disease, Ischemic Hypoxia and Chemical Hypoxia<br><br>Section D. Neuroimmunological Disorders – Anthony T. Reder <br><br>Chapter 15: Paraneoplastic Neurological Disorders<br>Chapter 16: Systemic Lupus Erythematosus: Descriptive Past and Mechanistic Future<br>Chapter 17: Progressive Multifocal Leukoencephalopathy<br>Chapter 18: Multiple Sclerosis<br>Chapter 19: Immune-Mediated Neuropathies<br>Chapter 20: Hashimoto Encephalopathy<br><br>Section E. Cerebrovascular Diseases – Lewis Morgenstern<br> <br>Chapter 21: Vascular Cognitive Impairment<br>Chapter 22: Cardioembolism<br>Chapter 23: Coagulation Disorders<br>Chapter 24: Clinical and Neurobiological Aspects of Stroke Recovery <br>Chapter 25: Non-Atherosclerotic Cerebral Vasculopathies<br>Chapter 26: Subarachnoid Hemorrhage<br>Chapter 27: Cerebral Ischemia: Molecular Mechanisms and Protective Therapies<br>Chapter 28: Intracerebral Hemorrhage and Intraventricular Hemorrhage-Induced Brain Injury<br><br>Section F. Paroxysmal Disorders – Timothy A. Pedley <br><br>Chapter 29: Idiopathic Epilepsies<br>Chapter 30: Paroxysmal Dyskinesia<br>Chapter 31: Neurobiology of Myoclonus<br>Chapter 32: Channelopathies of the Nervous System<br>Chapter 33: Migraine<br>Chapter 34: Temporal Lobe Epilepsy<br><br>Section G. Neoplastic Diseases – John Laterra <br><br>Chapter 35: CNS Metastases<br>Robert J. Weil<br><br>Chapter 36: Meningioma<br>Katrin Lamszus, Christian Hagel, and Manfred Westphal<br><br>Chapter 37: CNS Lymphoma<br>Corresponding Author: Dr. Batchelor<br><br>Chapter 38: Neurofibromatosis 1<br>Linda Piersall and David H. Gutmann<br><br>Chapter 39: Medulloblastoma and Primitive Neuroectodermal Tumors<br>Said Elshihabi and James T. Rutka<br><br>Chapter 40: Glioma<br>Anders I. Persson, QiWen Fan, Joanna J. Phillips, and William A. Weiss<br><br>Section H. Infectious Diseases – Richard T. Johnson <br><br>Chapter 41: Bacterial & Fungal<br>Chapter 42: Parasitic Infections<br>Chapter 43: Prion Diseases<br>Chapter 44: Central Nervous System Viral Infections: Clinical Aspects and Pathogenic Mechanisms<br><br>Section I. Motor Neuron Diseases – Eva L. Feldman <br><br>Chapter 45: Spinal Muscular Atrophy<br>Chapter 46: Amyotrophic Lateral Sclerosis-Like Syndromes Associated with Malignancy<br>Chapter 47: Amyotrophic Lateral Sclerosis (ALS): Idiopathic and Inherited<br>Chapter 48: Hereditary Spastic Paraplegia and Primary Lateral Sclerosis<br>Chapter 49: Poliomyelitis<br>Chapter 50: Spinobulbar Muscular Atrophy (Kennedy’s Disease)<br><br>Section J. Malformations and Developmental Disorders – Michael V. Johnston <br><br>Chapter 51: Neurobiology of Genetic Mental Retardation<br>Chapter 52: Cerebral Palsy<br>Chapter 53: Autism<br>Chapter 54: Neurobiology of Dyslexia<br>Chapter 55: Neonatal Brain Injuries<br>Chapter 56: Spina Bifida<br>Chapter 57: Circuits to Synapses: The Pathophysiology of Tourette Syndrome<br>Chapter 58: Attention Deficit Hyperactivity Disorder<br>Chapter 59: Congenital Hydrocephalus <br><br>Section K. Neurologic Manifestations of Medical Diseases – John J. Caronna <br><br>Chapter 60: Hematological Disorders<br>Chapter 61: Renal Disease<br>Chapter 62: Diabetes and Endocrine Disorders<br>Chapter 63: Mechanisms and Consequences of CNS Hypoxia<br>Chapter 64: Gastroenterologic and Hepatic Diseases and Their Effects on CNS<br>Chapter 65: Sarcoidosis<br><br>Section L. Sleep Disorders – Emmanuel Mignot <br><br>Chapter 66: REM Sleep Behavior Disorder<br>Chapter 67: The Neurobiology of Narcolepsy and Hypersomnia<br>Chapter 68: Restless Legs Syndrome and Periodic Leg Movement<br>Chapter 69: Obstructive Sleep Apnea<br>Chapter 70: The Neurobiology of Insomnia<br><br>Section M. Substance Abuse and Basic Toxicology – John C. M. Brust <br> <br>Chapter 71: Organic Chemicals<br>Chapter 72: Metals<br>Chapter 73: Drug Addiction<br><br>Section N. Imaging the Nervous System – John C. Mazziotta <br><br>Chapter 74: Assessment of Neurobiological Diseases with Magnetic Resonance Spectroscopy<br>Chapter 75: Magnetic Resonance Imaging<br>Chapter 76: Neurovascular CT Angiography<br>Chapter 77: PET Imaging in Parkinson's Disease and Other Neurodegenerative Disorders<br>Chapter 78: Single Photon Emission Computed Tomography (SPECT)<br>Chapter 79: Functional Magnetic Resonance Imaging (fMRI)<br><br>Part II. Peripheral Nervous System<br><br>Section O. Peripheral Neuropathies – James Russell <br> <br>Chapter 80: Diabetic and Metabolic Neuropathies<br>Chapter 81: Aquired Inflammatory Demyelinating and Axonal Neuropathies<br>Chapter 82: Toxic and Drug-Induced Neuropathies<br>Chapter 83: Hereditary Neuropathies<br>Chapter 84: Neurological Manifestations of Vasculitis<br>Chapter 85: Neuropathies Associated with Infections<br><br>Section P. Myopathies and neuromuscular junction disorders – Charles A. Thornton <br><br>Chapter 86: The Muscular Dystrophies<br>Chapter 87: Myasthenia Gravis and Myasthenic Syndromes<br>Chapter 88: Myopathies and Neuromuscular Junction Disorders<br>Chapter 89: Immunobiology of Autoimmune Inflammatory Myopathies<br><br>Section Q. Autonomic Disorders – Phillip A. Low <br><br>Chapter 90: Central Autonomic Network<br>Chapter 91: Autonomic Neuropathies<br>Chapter 92: Thermoregulation and its Disorders<br>Chapter 93: Control of Blood Pressure-Normal and Abnormal<br><br>Section R. Pain – Kenneth L. Casey <br><br>Chapter 94: Neoplasm-Induced Pain<br>Chapter 95: Pain Associated with the Autonomic Nervous System<br>Chapter 96: Post-Herpetic Neuralgia<br>Chapter 97: Central Post-Stroke Pain