GABAb Receptor Pharmacology: A Tribute to Norman Bowery

<p>1. Historical Perspective and Emergence of the GABA<SUB>B</SUB> Receptor<br>Norman Bowery<br>2. Chemistry of GABA<SUB>B</SUB> Receptor Ligands<br>Wolfgang Froestl<br>3. Heterodimerization of the GABA<SUB>B</SUB> Receptor - Implications for GPCR Signaling and Drug Discovery<br>Fiona H. Marshall and Steven M. Foord<br>4. Mechanisms of GABA<SUB>B</SUB> Receptor Exocytosis, Endocytosis and Degradation<br>Deitmar Benke<br>5. Functional Modulation of GABA<SUB>B</SUB> Receptors by Protein Kinases and Receptor Trafficking<br>Miho Terunuma, Andres Couve, Menelas N. Pangalos, and Stephen J. Moss<br>6. GABA<SUB>B</SUB> Receptor Coupling to G Proteins and Ion Channels<br>Claire Padgett and Paul A. Slesinger<br>7. GABA<SUB>B</SUB> Receptor-mediated Modulation of Metabotropic Glutamate Signaling and Synaptic Plasticity in Central Neurons<br>M. Kano and Toshihide Tabata<br>8. GABA Transporter GAT1: A Crucial Determinant of GABA<SUB>B</SUB> Receptor Activation in Cortical Circuits?<br>Guillermo Gonzalez-Burgos<br>9. The Role of GABA<SUB>B</SUB> Receptors in Cortical Network Activity<br>Michael M. Kohl and Ole Paulsen<br>10. GABA<SUB>B</SUB> Receptors: Physiology Functions and Mechanisms of Diversity<br>Andree Pinard, Riad Seddik, and Bernhard Bettler<br>11. Role of GABAB Receptors in Autonomic Control of Systemic Blood Pressure<br>De-Pei Li and Hui-Lin Pan<br>12. GABA<SUB>B</SUB> Receptor Agonism as a Novel Therapeutic Modality in the Treatment of Gastroesophageal Reflux Disease<br>Anders Lehmann, Jorgen Jensen, and Guy E. Boeckxstaens<br>13. GABA<SUB>B</SUB> Receptors in Reward Processes<br>Styliani Vlachou and Athina Markou<br>14. GABA<SUB>B</SUB> Receptors in Addiction and Its Treatment<br>David J. Nutt, Anne Lingford-Hughes, Laurence John Reed, and Robin J. Tyacke<br>15. GABA<SUB>B</SUB> - GIRK2 Mediated Signaling in Down Syndrome<br>Nathan Cramer, Tyler Best, and Zygmunt Galdzicki<br>16. GABA<SUB>B</SUB> Receptors and Depression: Current Status<br>John F. Cryan and David A. Slattery<br>17. GABA<SUB>B</SUB> Receptors in Drosophila<br>Hari Manev and Svetlana Dzitoyeva</p>