Gerard Karsenty
Elsevier Science
e druk, 2012
9780124157842
Translational Endocrinology of Bone
Reproduction, Metabolism, and the Central Nervous System
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
2012
ISBN13: 9780124157842
Rubricering
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
The use of model organisms together with the power of genetics has profoundly affected our understanding of the physiology of one organ, the skeleton, in two distinct but complementary ways. This is the first translational reference to focus on these major conceptual advances in bone biology and their development in the clinic. Several advances have already been translated into therapies and others are being tested for diseases as different as osteoporosis, type-2 diabetes, and hypo-fertility. This book is a timely reference for both basic and clinical researchers in bone biology and endocrinology.
Specificaties
Inhoudsopgave
1. Introduction 2. Bone Remodelling & Regulation* 3. Food Intake of Bone Formation 4. Central Control of Bone Mass 5. Neuropeptide Y and Bone Formation6. Serotonin: The Central Link between Bone Mass and Energy Metabolism 6. Gut Serotonin Bone Formation 7. Gut Serotonin and Osteoporosis 8. Regulation of Bone Resoprtion by PPARGamma 10. Regulation of Energy Metabolism by Bone 11. Bone Marrow Fat and Bone Mass 12. Bone Mass and Energy Metabolism in Humans 13. Regulation of Fertility by Bone 14. Molecular Signaling by Osteocalcin 15. Regulation of Phosphate Metabolism by FGF23 16. The Clinical Use of FGF 23 17. Transcriptional Regulation of the Endocrine Function of Bone