Pharmacology of the Blood Brain Barrier: Targeting CNS Disorders

1. ABC Transporter Regulation by Signaling at the Blood–Brain Barrier: Relevance to Pharmacology<br>David S. Miller<br>2. P-glycoprotein Trafficking as a Therapeutic Target to Optimize CNS Drug Delivery<br>Thomas P. Davis, Lucy Sanchez-Covarubias and Margaret E. Tome<br>3. Functional Expression of Drug Transporters in Glial Cells: Potential Role on Drug Delivery to the CNS<br>Tamima Ashraf, Amy Kao and Reina Bendayan<br>4. Blood–Brain Barrier Na Transporters in Ischemic Stroke<br>Martha E. O’Donnell<br>5. Transcytosis of Macromolecules at the Blood–Brain Barrier<br>Jane E. Preston, N. Joan Abbott and David J. Begley<br>6. Drug Delivery to the Ischemic Brain<br>Brandon J. Thompson and Patrick T. Ronaldson<br>7. Delivery of Chemotherapeutics Across the Blood–Brain Barrier: Challenges and Advances<br>Nancy D. Doolittle, Leslie L. Muldoon, Aliana Y. Culp and Edward A. Neuwelt<br>8. Delivery of Antihuman African Trypanosomiasis Drugs Across the Blood–Brain and Blood–CSF Barriers<br>Gayathri N. Sekhar, Christopher P. Watson, Mehmet Fidanboylu, Lisa Sanderson and Sarah A. Thomas<br>9. Delivery of Therapeutic Peptides and Proteins to the CNS<br>Therese S. Salameh and William A. Banks<br>10. Engineering and Pharmacology of Blood–Brain Barrier-Permeable Bispecific Antibodies<br>Danica Stanimirovic, Kristin Kemmerich, Arsalan S. Haqqani and Graham K. Farrington<br>11. Pharmacological Significance of Prostaglandin E2 and D2 Transport at the Brain Barriers<br>Masanori Tachikawa, Ken-ichi Hosoya and Tetsuya Terasaki<br>12. Steroids and the Blood–Brain Barrier: Therapeutic Implications<br>Ken A. Witt and Karin E. Sandoval<br>13. Combination Approaches to Attenuate Hemorrhagic Transformation After tPA Thrombolytic Therapy in Patients with Poststroke Hyperglycemia/Diabetes<br>Xiang Fan, Yinghua Jiang, Zhanyang Yu, Jing Yuan, Xiaochuan Sun, Shuanglin Xiang, Eng H. Lo and Xiaoying Wang<br>14. Aging, the Metabolic Syndrome, and Ischemic Stroke: Redefining the Approach for Studying the Blood–Brain Barrier in a Complex Neurological Disease<br>Brandon P. Lucke-Wold, Aric F. Logsdon, Ryan C. Turner, Charles L. Rosen and Jason D. Huber<br>15. Drug Abuse and the Neurovascular Unit<br>Richard D. Egleton and Thomas Abbruscato