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Molecular Aspects of Alcohol and Nutrition

A Volume in the Molecular Nutrition Series

Specificaties
Gebonden, blz. | Engels
Elsevier Science | 2015
ISBN13: 9780128007730
Rubricering
Elsevier Science e druk, 2015 9780128007730
€ 112,54
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Molecular Aspects of Alcohol and Nutrition is a valuable resource for nutrition researchers and nutritionists who study or treat alcohol-related diseases. Experts from across the field of alcohol research explain how alcohol disrupts normal fat, carbohydrate, and protein metabolic processes occurring in the liver as well as other parts of the body.

The book discusses how this can lead to alcoholic liver disease (ALD) as well as contribute to the onset of Type 2 diabetes and the metabolic syndrome. It also explores how alcohol affects nutrient absorption in the gastrointestinal tract and can lead to anemia and reduced amounts of fat soluble vitamins.

This book explores both the primary and secondary consequences of alcohol consumption. Chapters in the first section investigate the basic science of alcohol metabolism – focusing on how alcohol and its toxic metabolites disrupt and impair normal nutrient regulation at the molecular level. Further chapters explore how alcohol affects many extra-hepatic organs and tissues as well as the secondary consequences of alcohol consumption such as reduced levels of minerals like magnesium, calcium, and trace elements like zinc.

Specificaties

ISBN13:9780128007730
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>Section 1. General and Introductory Aspects<br>1. Nutrients and Liver Energy Metabolism<br>  Daniel Gyamfi and Kwabena Owusu Danquah <br>2. Alcohol Metabolism: general aspects<br>  Reem Ghazali and Vinood B. Patel<br>Section 2. Molecular biology of the cell<br>3. Alcohol and aldehyde dehydrogenases: molecular aspects<br>  Kwabena Owusu Danquah<br>4. Apoptosis and alcohol <br>  F.A. Middleton<br>5. Pathogenic Mechanisms in Alcoholic Liver Disease (ALD): emerging role of Osteopontin  <br>  Wing-Kin Syn and Jason D. Coombes <br>6. The Role of CD36 in the Pathogenesis of Alcohol-Related Disease<br>  Caleb T. Epps, Robin D. Clugston, Amit Saha, William S. Blaner and Li-Shin Huang <br>7. Thiamine deficiency in alcoholics<br>  Ann M. Manzardo<br>8. Vitamin B regulation of Alcoholic Liver Disease<br>  Charles H. Halsted and Valentina Medici <br>9. Vitamin D and alcohol interactions and implication for bone<br>  Emilio Gonzalez-Reimers, Geraldine Quintero-Platt, Antonio Martinez-Riera and Francisco Santolaria-Fernandez <br>10. Antioxidant treatment of alcoholism<br>  Camila Siqueira Silva, Helio Vannucchi and Guilherme Vannucchi Portari <br>11. Selenium dietary supplementation and oxidative balance in alcoholism<br>  Olimpia Carreras, María Luisa Ojeda and Fatima Nogales <br>12. Role of zinc in alcoholic liver disease<br>  Zhanxiang Zhou<br>13. Interactions between alcohol and folate<br>  Bogdan Cylwik<br>14. Effects of Acetladehyde on intestinal barrier function<br>  D. Jonkers and Elhaseen Elamin <br>15. Cholesterol regulation by leptin in alcoholic liver disease<br>  Balasubramaniyan Vairappan<br>16. CRF system and alcohol consumption<br>  Andrey E. Ryabinin and William J. Giardino <br>17. Metabolic profiling approaches for biomarkers of ethanol intake<br>  Helen G. Gika and Ian D. Wilson <br>Section 3. Genetic machinery and its function<br>18. Gene expression in alcoholism: an overview<br>  Reem Ghazali and Vinood B. Patel <br>19. Cytochrome P4502E1 Gene Polymorphisms in alcoholics<br>  Tao Zeng and K.-Q. Xie <br>20. Genes associated with alcohol withdrawal <br>  Kesheng Wang and Liang Wang <br>21. Alcohol and epigenetic modulations <br>  Claudio D'Addario and Mauro Maccarrone <br>22. miRNA Expression in the alcoholic liver disease<br>  Shashi Bala<br>22. Alcohol and DNA Methylation<br>  Feng C. Zhou<br>24. Ethanol-mediated carcinogenesis molecular insights as an overview<br>  Helmut K. Seitz<br>25. Molecular link between alcohol and breast cancer: the role of salsolinol<br>  Mariko Murata, Kaoru Midorikawa and Shosuke Kawanishi <br>26. Ethanol impairs Phospholipase D signaling in astrocytes<br>  Ute Burkhardt and Jochen Klein <br>27. Metabolite changes in alcohol gonadotoxicity<br>  Ganna M. Shayakhmetova and Larysa B. Bondarenko <br>28. Hepcidin and iron dysregulation in alcoholics<br>  Kosha Mehta and Vinood B. Patel</p>
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        Molecular Aspects of Alcohol and Nutrition