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Biometals in Neurodegenerative Diseases

Mechanisms and Therapeutics

Specificaties
Gebonden, blz. | Engels
Elsevier Science | 2017
ISBN13: 9780128045626
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Elsevier Science e druk, 2017 9780128045626
€ 166,60
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Biometals in Neurodegenerative Diseases: Mechanisms and Therapeutics is an authoritative and timely resource bringing together the major findings in the field for ease of access to those working in the field or with an interest in metals and their role in brain function, disease, and as therapeutic targets. Chapters cover metals in Alzheimer’s Disease, Parkinson’s Disease, Motor Neuron Disease, Autism and lysosomal storage disorders.

This book is written for academic researchers, clinicians and advanced graduate students studying or treating patients in neurodegeneration, neurochemistry, neurology and neurotoxicology. The scientific literature in this field is advancing rapidly, with approximately 300 publications per year adding to our knowledge of how biometals contribute to neurodegenerative diseases.

Despite this rapid increase in our understanding of biometals in brain disease, the fields of biomedicine and neuroscience have often overlooked this information. The need to bring the research on biometals in neurodegeneration to the forefront of biomedical research is essential in order to understand neurodegenerative disease processes and develop effective therapeutics.

Specificaties

ISBN13:9780128045626
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1. Biometals and Alzheimer’s Disease<br>2. Copper in Alzheimer’s Disease<br>3. The Role of Selenium in Neurodegenerative Diseases<br>4. Does HFE Genotype Impact Macrophage Phenotype in Disease Process and Therapeutic Response?<br>5. Chemical Elements and Oxidative Status in Neuroinflammation<br>6. Metals and Neuroinflammation<br>7. Metals and Prions: Twenty Years of Mining the Awe<br>8. Manganese and Neurodegeneration<br>9. Zinc in Autism<br>10. Metals and Motor Neuron Disease<br>11. Metals and Lysosomal Storage Disorders<br>12. Developmental Exposure to Metals and its Contribution to Age-Related Neurodegeneration<br>13. Metal Biology Associated with Huntington’s Disease<br>14. Metal-Binding to Amyloid-β Peptide: Coordination, Aggregation, and Reactive Oxygen Species Production<br>15. Metals and Mitochondria in Neurodegeneration<br>16. Metal Transporters in Neurodegeneration<br>17. Metal Imaging in the Brain<br>18. Metalloregulation of Protein Clearance: New Therapeutic Avenues for Neurodegenerative Diseases<br>19. Metals and Autophagy in Neurotoxicity<br>20. An Overview of Multifunctional Metal Chelators as Potential Treatments for Neurodegenerative Diseases<br>21. Abnormal Function of Metalloproteins Underlies Most Neurodegenerative Diseases</p>
€ 166,60
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        Biometals in Neurodegenerative Diseases