The Molecular and Cellular Basis of Neurodegenerative Diseases

Underlying Mechanisms

Specificaties
Gebonden, blz. | Engels
Elsevier Science | 2018
ISBN13: 9780128113042
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Elsevier Science e druk, 2018 9780128113042
€ 106,54
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The Molecular and Cellular Basis of Neurodegenerative Diseases: Underlying Mechanisms presents the pathology, genetics, biochemistry and cell biology of the major human neurodegenerative diseases, including Alzheimer’s, Parkinson’s, frontotemporal dementia, ALS, Huntington’s, and prion diseases. Edited and authored by internationally recognized leaders in the field, the book's chapters explore their pathogenic commonalities and differences, also including discussions of animal models and prospects for therapeutics. Diseases are presented first, with common mechanisms later. Individual chapters discuss each major neurodegenerative disease, integrating this information to offer multiple molecular and cellular mechanisms that diseases may have in common.

This book provides readers with a timely update on this rapidly advancing area of investigation, presenting an invaluable resource for researchers in the field.

Specificaties

ISBN13:9780128113042
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1. General Overview<br>2. Prion Diseases<br>3. Alzheimer’s disease: towards a quantitative biological approach in describing its natural history and underlying mechanisms<br>4. Neurodegeneration and the ordered assembly of Tau <br>5. ALS and Other TDP43 Proteinopathies <br>6. Parkinson’s Disease and Other Synucleinopathies<br>7. Huntington’s Disease and Other Polyglutamine Disorders <br>8. Prion-like propagation in Neurodegenerative Diseases <br>9. Neurodegenerative Diseases as Protein Folding Disorders <br>10. Heat shock proteins and protein quality control in Alzheimer's disease<br>11. Neurodegenerative Diseases and Autophagy <br>12. Neurodegenerative Diseases and Axonal Transport <br>13. Mitochondrial Function and Neurodegenerative Diseases<br>14. Neurodegenerative Diseases and Non-cell autonomous toxicity <br>15. Neurodegenerative Diseases and RNA-mediated toxicity <br>16. Neuroinflammation in Age-Related Neurodegenerative Diseases<br>17. Neurodegenerative Diseases and the Aging Brain</p>
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        The Molecular and Cellular Basis of Neurodegenerative Diseases