Mansoor M. Amiji,
Rajagopal Ramesh
Elsevier Science
e druk, 2018
9780128127742
Diagnostic and Therapeutic Applications of Exosomes in Cancer
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
2018
ISBN13: 9780128127742
Rubricering
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Diagnostic and Therapeutic Applications of Exosomes in Cancer evaluates the potential of exosome content manipulation in the development of novel therapeutics. In recent years, exosomes, the small vesicles produced by all cell types, have been identified as contributors to cancer growth and metastasis. However, due to their unique biophysical properties, they are also being tested for use in therapeutic design and delivery, as well as in diagnostics. This book presents a comprehensive analysis on exosomes, with a main emphasis on their biogenesis and signaling, use as biomarkers, and as tools for imaging, drug delivery and the treatment of cancer.
Specificaties
Inhoudsopgave
<p>1. Introduction to Exosomes in Cancer<br>2. Extracellular Vesicle Biogenesis in Cancer<br>3. Composition, Physicochemical and Biological properties of Exosomes Secreted from Cancer Cells<br>4. Heterogeneity of Tumor Exosomes – Role in Personalized Medicine<br>5. Proteomic Profiling of Tumor Exosomes<br>6. Nucleic Acid Profiling in Exosomes<br>7. Nanotechnology Platforms for Cancer Exosome Analyses<br>8. Microfluidics and Tumor Exosomes<br>9. Exosomal RNA as Biomarkers: Role in Cancer Prevention<br>10. Diagnostic Potential of Tumor Exosomes<br>11. Biodistribution of Tumor Derived Exosomes<br>12. Tumor-Derived Exosomes as Vehicles Mediating Immune Suppression in Cancer<br>13. Exosome Uptake and Cellular Reprogramming in the Tumor Microenvironment<br>14. Exosomes and Intercellular Conduits: Communication between Tumor Cells and Fibroblasts in the Microenvironment<br>15. Exosomes in Tumor Angiogenesis<br>16. Role of Exosomes in Development of Pre-Metastatic Niche<br>17. Role of Exosomes in Tumor Metastasis<br>18. Exosomes and Tumor Drug Resistance<br>19. Exosomes in Cancer Immunotherapy<br>20. Extracellular Vesicles as Vehicles of B Cell Antigen Presentation: Implications for Cancer Vaccine Therapies<br>21. Translational Potential of Tumor Exosomes in Diagnosis and Therapy<br>22. Perspective on Cancer Exosomes in the Future</p>