Oxidative Stress

Eustress and Distress

Specificaties
Paperback, blz. | Engels
Elsevier Science | 2019
ISBN13: 9780128186060
Rubricering
Elsevier Science e druk, 2019 9780128186060
€ 211,00
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Samenvatting

Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress within the framework of redox biology and translational medicine. It describes eustress and distress in molecular terms and with novel imaging and chemogenetic approaches in four sections:

A conceptual framework for studying oxidative stress.

Processes and oxidative stress responses. Signaling in major enzyme systems (oxidative eustress), and damaging modification of biomolecules (oxidative distress).

The exposome addresses lifelong exposure and impact on health, nutrient sensing, exercise and environmental pollution.

Health and disease processes, including ischemia-reperfusion injury, developmental and psychological disorders, hepatic encephalopathy, skeletal muscle disorders, pulmonary disease, gut disease, organ fibrosis, and cancer.

Oxidative Stress: Eustress and Distress is an informative resource useful for active researchers and students in biochemistry, molecular biology, medicinal chemistry, pharmaceutical science, nutrition, exercise physiology, analytical chemistry, cell biology, pharmacology, clinical medicine, and environmental science.

Specificaties

ISBN13:9780128186060
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>I. Conceptual<br>1. Oxidative Eustress and Oxidative Distress: Introductory Remarks<br>2. Epistemological challenges of the Oxidative Stress Theory of Disease and the problem of biomarkers<br>3. Systems Biology and Network medicine: An Integrated Approach to Redox Biology and Pathobiology<br>4. The Reactive Species Interactome</p> <p>II. Oxidative Eustress and Distress: Processes and Responses<br>5. Oxidative stress and the early co-evolution of life and biospheric oxygen<br>6. How imaging transforms our understanding of oxidative stress<br>7. In vivo applications of chemogenetics in redox (patho)biology<br>8. Quantification of H2O2 in cells: methods and significance<br>9. The Keap1-Nrf2 pathway: From Mechanism to Medical Applications<br>10. Ferroptosis: physiological and pathophysiological aspects<br>11. Aquaporins: gatekeepers in the borders of oxidative stress and redox signalling<br>12. Extracellular superoxide dismutase (SOD3): an antioxidant or prooxidant in the extracellular space?<br>13. Protein S-glutathionylation and the regulation of cellular functions<br>14. Dual stressor effects of lipid oxidation and antioxidants<br>15. Oxidized phospholipid signaling: distress to eustress<br>16. Redox regulation of protein kinase signaling<br>17. FoxO transcription factors in the control of redox homeostasis and fuel metabolism<br>18. Oxidatively generated DNA base modifications: relation to eustress and distress<br>19. Light-Initiated Oxidative Stress<br>20. Nutritional Protection against Photooxidative Stress in Human Skin and Eye</p> <p>III. Exposome <br>21. Mechanisms integrating lifelong exposure and health<br>22. Nutrient Sensing, the Oxidative Stress Response, and Stem Cell Aging<br>23. How exercise induces oxidative eustress<br>24. Metabolomics as a tool to unravel the oxidative stress-induced toxicity of ambient air pollutants<br>25. Traffic-related environmental risk factors and their impact on oxidative stress and cardiovascular health</p> <p>IV. Oxidative Stress in Health and Disease Processes<br>26. Mitochondrial ROS production during ischemia-reperfusion injury <br>27. Redox signaling in cellular differentiation<br>28. Redox regulated brain development<br>29. Eustress, Distress, and Oxidative Stress: Promising Pathways for Mind-Body Medicine<br>30. Reactive Oxygen Species and Cancer<br>31. Perspectives of TrxR1-based cancer therapies<br>32. Oxidative/nitrosative stress and hepatic encephalopathy<br>33. ROS Signaling in Complex Systems: The Gut<br>34. Oxidative stress in skeletal muscle: Unravelling the potential beneficial and deleterious roles of reactive oxygen species<br>35. Redox Mechanisms in Pulmonary Disease: Emphasis on Pulmonary Fibrosis<br>36. Dicarbonyl stress and the glyoxalase system<br>37. Redox distress in organ fibrosis: the role of non-coding RNAs</p>
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