Hematopoietic Stem Cell Transplantation for Neurologic Diseases
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
2024
ISBN13: 9780323902427
Rubricering
Onderdeel van serie
Handbook of Clinical Neurology
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Hematopoietic Stem Cell Transplantation for Neurological Diseases (HSCT), Volume 201 provides the latest information on what has been evaluated as a possible therapeutic tool in severe autoimmune diseases for the last 20 years. In the neurological field, HSCT has been widely investigated for the treatment of multiple sclerosis and evidence is accumulating about its potential use in neuromyelitis optica, stiff person syndrome, myasthenia gravis, and many immune neuropathies. Besides their strong clinical relevance, studies on HSCT in neurological diseases have contributed to new insights on the pathological mechanisms underlying CNS autoimmunity, hence this volume summarizes that research.
Specificaties
Inhoudsopgave
1. Introduction to HSCT for neurologic diseases<br>2. Modification of T and B cell-associated immuno-pathological mechanisms in multiple sclerosis by disease modifying therapies: achievements and opportunities<br>3. The hematopoietic niche and the autoreactive memory in autoimmune disorders<br>4. The preclinical data and immunological rationale for hematopoietic stem cell transplantation in autoimmunity<br>5. Immune cell reconstitution following autologous hematopoietic stem cell transplantation in multiple sclerosis<br>6. Immune reconstitution in rheumatic disease patients after autologous hematopoietic stem cell transplantation<br>7. The role of chemotherapy in hematopoietic stem cell transplantation HSCT for autoimmune disorders: from lymphoablative to myeloablative conditioning protocols<br>8. The HSCT procedure (I): mobilization, collection, manipulation and cryopreservation of HSC<br>9. The HSCT procedure (II): conditioning, hemopoietic stem cell infusion, supportive care and monitoring<br>10. Early and late complications of HSCT<br>11. Hematopoietic Stem Cell Transplantation for Multiple Sclerosis<br>12. Hematopoietic stem cell transplantation for neuromyelitis optica spectrum disorder. Can immune tolerance be re-established?<br>13. Hematopoietic stem cell transplantation (HSCT) for chronic inflammatory demyelinating polyradiculoneuropathy (CIDP): Is it CIDP?<br>14. HSCT for Stiff Person Syndrome and Myasthenia Gravis<br>15. Autologous hematopoietic stem cell transplantation for pediatric autoimmune neurologic disorders<br>16. HSCT for systemic autoimmune diseases with neurologic involvement<br>17. Hematopoetic Stem Cell Therapy and Ex Vivo Gene Therapy for X-linked Adrenoleukodystrophy<br>18. Economics of Hematopoietic Stem Cell Transplant in immune-mediated neurologic autoimmune diseases<br>19. The EBMT-ADWP and the CIBMTR<br>20. Ongoing randomized clinical trials on HSCT in multiple sclerosis