Poly(ADP-Ribosyl)ation

Specificaties
Gebonden, 246 blz. | Engels
Springer US | 2006e druk, 2006
ISBN13: 9780387333717
Rubricering
Springer US 2006e druk, 2006 9780387333717
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Samenvatting

Poly(ADP-Ribosyl)ation comprises 19 chapters written by leading international experts in the field and is richly illustrated. Extensive bibliography is given in each chapter.

Specificaties

ISBN13:9780387333717
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:246
Uitgever:Springer US
Druk:2006

Inhoudsopgave

Enzymes in Poly(ADP-Ribose) Metabolism.- PARP-2: Structure-Function Relationship.- Targeting the Poly (ADP-Ribose) Glycohydrolase (PARG) Gene in Mammals.- DNA Damage Signaling through Poly(ADP-Ribose).- Roles of Poly(ADP-Ribose) Metabolism in the Regulation of Centrosome Duplication and in the Maintenance of Neuronal Integrity.- Functional Interactions of PARP-1 with p53.- Dynamic Interaction between PARP-1, PCNA and p21waf1/cip1.- PARP-1 as Novel Coactivator of NF-?B in Inflammatory Disorders.- PARP and Epigenetic Regulation.- PARP and the Release of Apoptosis-Inducing Factor from Mitochondria.- Genome Degradation by DNAS1L3 Endonuclease.- NAD: Metabolism and Regulatory Functions.- PARP-1 and the Shape of Cell Death.- Poly(ADP-Ribose) Polymerase (PARP) and Excitotoxicity.- Poly(ADP-Ribose) Polymerase and Ischemia-Reperfusion Injury.- Role of Poly(ADP-Ribose) Polymerase Activation in the Pathogenesis of Inflammation and Circulatory Shock.- Role of Poly-ADP-Ribosylation in Cancer Development.- PARP Inhibitors and Cancer Therapy.- Poly(ADP-Ribosyl)ation and Aging.
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        Poly(ADP-Ribosyl)ation