Handbook of Molecular Force Spectroscopy
Samenvatting
Researchers in academia and industry who are interested in techniques for measuring intermolecular forces will find this an essential text. It presents a review of modern force spectroscopy, including fundamentals of intermolecular forces, technical aspects of the force measurements, and practical applications. The handbook begins with a review of the fundamental physics of loading single and multiple chemical bonds on the nanometer scale. It contains a discussion of thermodynamic and kinetic models of binding forces and dissipation effects in nanoscale molecular contacts, covers practical aspects of modern single-molecule level techniques, and concludes with applications of force spectroscopy to chemical and biological processes. Computer modeling of force spectroscopy experiments is also addressed.
Specificaties
Inhoudsopgave
<P>Surface force apparatus measurements of molecular forces in biological adhesion <BR><STRONG>(Deborah Leckband, Univ. of Illinois, Urbana-Champaign)</STRONG> </P>
<P>Force spectroscopy with optical and magnetic tweezers <STRONG>(Richard Conroy, Harvard University)</STRONG> </P>
<P>Chemical Force Microscopy 1: Nanoscale probing of fundamental chemical interactions <STRONG>(Aleksandr Noy, LLNL, Dmitry V. Vezenov, Harvard University, and Charles M. Lieber, Harvard University)</STRONG> </P>
<P>Chemical Force Microscopy 2: Interactions in complex molecular assemblies <STRONG>(Dmitry V. Vezenov, Harvard University, Aleksandr Noy, LLNL, and Charles M. Lieber, Harvard University)</STRONG> </P>
<P>Dynamic force spectroscopy with the atomic force microscope <STRONG>(Phil Williams,</STRONG> <STRONG>University of Nottingham)</STRONG> </P>
<P>Simulation in force spectroscopy <STRONG>(David L. Patrick, Western Washington University)</STRONG> </P>
<P>Probe tip functionalization: applications to chemical force microscopy <STRONG>(Craig D. Blanchard, Albert Loui, and Timothy V. Ratto, LLNL)</STRONG> </P>
<P>The dynamical response of proteins under force <STRONG>(Kirstine L. Anderson, Sheena E. Radford, D. Alastair Smith, and David J. Brockwell, University of Leeds)</STRONG> </P>
<P>Counting and breaking single bonds: Dynamic force spectroscopy in tethered single molecule systems <STRONG>(Todd A. Sulchek, Raymond W. Friddle, and Aleksandr Noy, LLNL)</STRONG> </P>
<P>Direct mapping of intermolecular interaction potentials <STRONG>(Paul D. Ashby, MIT)</STRONG></P>