Meer over Jacquelyn L. Banasik

Jacquelyn L. Banasik

Pathophysiology

Name: Pathophysiology
Author: Jacquelyn L. Banasik

Specificaties

Paperback, blz. | Engels

Elsevier Health Sciences | 2026

ISBN13: 9780443125232

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Elsevier Health Sciences e druk, 2026 9780443125232

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Gain the in-depth understanding of pathophysiology you need to guide your patient care! Using a systems approach, Pathophysiology, 8th Edition, examines the etiology, pathogenesis, clinical manifestations, and treatment of diseases and disorders. The book begins with a review of normal anatomy and physiology, followed by pathophysiology and application of concepts to specific disorders. Each chapter includes a discussion of the disease processes and abnormalities that may occur, with a focus on the pathophysiologic concepts involved. Written by a team of expert contributors led by Jacquelyn Banasik, this text emphasizes the major pathophysiology concepts relevant to clinical practice while not overwhelming the reader with minute detail.Clear, easy-to-read writing style emphasizes critical thinking, and includes many tables, boxes, and figures to highlight key contentThorough updates include information on the newest scientific findings and advances in treatment, more than 100 new figures for improved clarity, and moreMore than 1,000 full-color photos and illustrations help to clarify complex pathophysiological conceptsGlobal Health Care boxes summarize topics such as COVID-19, HIV/AIDS, Ebola, tropical diseases, and more, with information on prevalence, mechanism of disease and transmissionPediatric and Older Adult Considerations boxes address age-related changes associated with specific body systemsUseful learning resources include chapter outlines, bolded key terms, key questions, Key Points boxes, Clinical Judgment challenges, and chapter summariesNEW! Updated content throughout the book reflects the latest research and thinking in pathophysiology

Specificaties

ISBN13:9780443125232

Taal:Engels

Bindwijze:Paperback

Uitgever:Elsevier Health Sciences

Inhoudsopgave

UNIT I Pathophysiologic Processes 1 Introduction to Pathophysiology Framework for Pathophysiology Concepts of Normality in Health and Disease Epidemiology 2 Homeostasis Allostasis and Adaptive Responses to Stressors Homeostasis and Allostasis Stress as a Concept Neurohormonal Mediators of Stress and Adaptation Adaptation Coping and Illness UNIT II Cellular Function 3 Cell Structure and Function Plasma Membrane Organization of Cellular Compartments Cellular Metabolism Functions of the Plasma Membrane Intercellular Communication and Growth 4 Cell Injury Aging and Death Reversible Cell Injury Cellular Adaptation Irreversible Cell Injury Etiology of Cellular Injury Aging Somatic Death 5 Genome Structure Regulation and Tissue Differentiation Structure and Function of Deoxyribonucleic Acid Regulation of the Genome Differentiation of Tissues 6 Genetic and Developmental Disorders Principles of Inheritance Genetic Disorders Chromosomal Abnormalities Mendelian Single-Gene Disorders Nonmendelian Single-Gene Disorders Polygenic and Multifactorial Disorders Environmentally Induced Congenital Disorders Diagnosis Counseling and Gene Therapy 7 Neoplasia Benign Versus Malignant Growth Epidemiology and Cancer Risk Factors Genetic Mechanisms of Cancer Multistep Nature of Carcinogenesis Invasion and Metastasis Effects of Cancer On the Body Cancer Therapy UNIT III Defense 8 Infectious Processes Host-Microbe Relationship Transmission of Infection Types of Pathogenic Organisms 9 Inflammation and Immunity Components of the Immune System Epithelial Barriers Mononuclear Phagocyte System Lymphoid System Leukocytes Chemical Mediators of Immune Function Innate Defenses and Inflammation Inflammation Healing Inflammatory Exudates Systemic Manifestations of Inflammation Specific Adaptive Immunity Major Histocompatibility Complex Antigen Presentation By Major Histocompatibility Complex Mechanisms of Cell-Mediated Immunity Mechanisms of Humoral Immunity Antibody Structure Passive and Active Immunity Integrated Function and Regulation of the Immune System Integrated Response to Microbial Antigen Integrated Response to Viral Antigen Regulation of Immune Function 10 Alterations in Immune Function Excessive Immune Responses Autoimmunity Hypersensitivity Deficient Immune Responses Primary Immunodeficiency Disorders Secondary Immunodeficiency Disorders 11 Malignant Disorders of White Blood Cells Classification of Hematologic Neoplasms Etiology of Myeloid and Lymphoid Neoplasms General Principles of Management Myeloid Neoplasms Lymphoid Neoplasms 12 HIV Disease and Aids Epidemiology Etiology Pathogenesis Diagnostic Testing Monitoring the Progression of HIV Clinical Manifestations Treatment UNIT IV Oxygen Transport Blood Coagulation Blood Flow and Blood Pressure 13 Alterations in Oxygen Transport Composition of Blood Structure and Function of Red Blood Cells Gas Transport and Acid-Base Balance Anemia Anemia Related to Decreased Red Cell Production Anemia Related to Inherited Disorders of the Red Cell Anemia Related to Extrinsic Red Cell Destruction or Loss Polycythemia 14 Alterations in Hemostasis and Blood Coagulation The Process of Hemostasis Evaluation of Hemostasis and Coagulation Vascular and Platelet Disorders Coagulation Disorders 15 Alterations in Blood Flow Organization of the Circulatory and Lymphatic Systems Principles of Flow Control of Flow General Mechanisms that Cause Altered Flow Alterations in Arterial Flow Alterations in Venous Flow Alterations in Lymphatic Flow 16 Alterations in Blood Pressure Arterial Blood Pressure Mechanisms of Blood Pressure Regulation Hypertension Low Blood Pressure UNIT V Cardiac Function 17 Cardiac Function Cardiovascular Anatomy Cardiac Cycle Coronary Circulation Cardiac Myocytes Molecular Basis of Contraction Cardiac Energy Metabolism Cardiac Electrophysiology Electrocardiography Determinants of Cardiac Output Endocrine Function of the Heart Tests of Cardiac Function 18 Alterations in Cardiac Function Coronary Heart Disease Endocardial and Valvular Diseases Myocardial Diseases Pericardial Diseases Congenital Heart Diseases 19 Heart Failure and Dysrhythmias Heart Failure Cardiac Dysrhythmias 20 Shock Pathogenesis of Shock Types of Shock Assessment and Hemodynamic Monitoring Complications of Shock UNIT VI Respiratory Function 21 Respiratory Function and Alterations in Gas Exchange Functional Anatomy Ventilation Pulmonary Blood Flow Diffusion and Transport of Respiratory Gases Alterations in Pulmonary Function Diagnostic Tests Alterations in Pulmonary Vasculature Pulmonary Malignancies 22 Obstructive Pulmonary Disorders Obstruction From Conditions in the Wall of the Lumen Obstruction Related to Loss of Lung Parenchyma Obstruction of the Airway Lumen 23 Restrictive Pulmonary Disorders Lung Parenchyma Disorders Atelectatic Disorders Pleural Space Disorders Neuromuscular Chest Wall and Obesity Disorders Infection or Inflammation of the Lung UNIT VII Fluid Electrolyte and Acid-Base Homeostasis 24 Fluid and Electrolyte Homeostasis and Imbalances Body Fluid Homeostasis Fluid Imbalances Principles of Electrolyte Homeostasis Electrolyte Imbalances 25 Acid-Base Homeostasis and Imbalances Linda Felver Acid-Base Homeostasis Acid-Base Imbalances UNIT VIII Renal and Bladder Function 26 Renal Function Renal Anatomy Overview of Nephron Structure and Function Regulation of Glomerular Filtration Transport Across Renal Tubules Regulation of Blood Volume and Osmolality Endocrine Functions Age-Related Changes in Renal Function Tests of Renal Structure and Function 27 Intrarenal Disorders Common Manifestations of Kidney Disease Congenital Abnormalities Neoplasms Infection Obstruction Glomerular Disorders (Glomerulopathies) 28 Acute Kidney Injury and Chronic Kidney Disease Acute Kidney Injury Chronic Kidney Disease Clinical Management 29 Disorders of the Lower Urinary Tract Lower Urinary Tract Lower Urinary Tract Symptoms and Syndromes Neurogenic Bladder Congenital Disorders Neoplasms Inflammation and Infection Obstruction UNIT IX Genital and Reproductive Function 30 Male Genital and Reproductive Function Courtney Foss Anatomy Embryology Male Reproductive Physiology 31 Alterations in Male Genital and Reproductive Function Disorders of the Penis and Male Urethra Disorders of the Scrotum and Testes Disorders of the Prostate 32 Female Genital and Reproductive Function Reproductive Structures Menstrual Cycle Breast Pregnancy Menopause 33 Alterations in Female Genital and Reproductive Function Menstrual Disorders Alterations in Uterine Position and Pelvic Support Inflammation and Infection of the Female Reproductive Tract Benign Growths and Aberrant Tissue of the Female Reproductive Tract Cancer of the Female Genital Structures Disorders of Pregnancy Disorders of the Breast 34 Sexually Transmitted Infections Urethritis Cervicitis Salpingitis and Pelvic Inflammatory Disease Diseases With Systemic Involvement Diseases With Localized Lesions Enteric Infections UNIT X Gastrointestinal Function 35 Gastrointestinal Function Structure and Organization of the Gastrointestinal Tract Gastrointestinal Motility Secretory Function Digestion and Absorption Gastrointestinal Function Across the Life Span 36 Gastrointestinal Disorders Manifestations of Gastrointestinal Tract Disorders Disorders of the Mouth and Esophagus Oral Infections Esophageal Disorders Alterations in the Integrity of the Gastrointestinal Tract Wall Inflammation of the Stomach and Intestines Inflammatory Bowel Disease Enterocolitis Alterations in Motility and Malabsorption of the Gastrointestinal Tract Motility Disorders Mucosal Malabsorption Disorders Malabsorption Disorders After Surgical Intervention Neoplasms of the Gastrointestinal Tract Esophageal Gastric and Small Intestinal Cancers Colonic Polyps and Colon Cancer Psychosocial Aspects of Gastrointestinal Disorders 37 Alterations in Function of the Gallbladder and Exocrine Pancreas Anatomy and Physiology of the Pancreaticobiliary System Disorders of the Gallbladder Disorders of the Pancreas 38 Liver Diseases Structure and Function of the Liver General Manifestations of Liver Disease Disorders of the Liver Cirrhosis Toxic Liver Disorders Other Structural Liver Conditions Transplantation Liver Diseases and Pediatric Considerations Liver Diseases and Geriatric Considerations UNIT XI Endocrine Function Metabolism and Nutrition 39 Endocrine Physiology and Mechanisms of Hypothalamic Pituitary Regulation Hormone Structure and Action Hormone Regulation Hypothalamic-Pituitary Endocrine System Thyroid Hormones Steroid Hormones Categories of Endocrine Disease 40 Disorders of Endocrine Function Basic Concepts of Endocrine Disorders Growth Hormone Disorders Thyroid Hormone Disorders Adrenocortical Hormone Disorders Adrenal Medulla Disorder Parathyroid Gland Disorders Antidiuretic Hormone Disorders 41 Diabetes Mellitus Regulation of Glucose Metabolism Glucose Intolerance Disorders Clinical Manifestations and Complications Treatment and Education Pediatric Considerations Geriatric Considerations 42 Alterations in Metabolism and Nutrition Metabolic Processes Nutrient Metabolism Regulation of Appetite and Nutrient Metabolism Obesity and Metabolic Syndrome Metabolic Responses to Starvation and Physiologic Stress Nutritional Considerations for Aging and Altered Health States UNIT XII Neural Function 43 Structure and Function of the Nervous System Structural Organization Central Nervous System Peripheral Nervous System Autonomic Nervous System Neuronal Structure and Function Neurons and Supportive Cells Neuronal Communication Neural Development Aging and Injury Sensory Function Sensory Receptors Sensory Pathways Somatosensory Cortex Motor Function Motor Neurons Spinal Reflexes Central Control of Motor Function Consciousness Memory and Sleep Consciousness and Memory Sleep 44 Acute Disorders of Brain Function Mechanisms of Brain Injury Manifestations of Brain Injury Traumatic Brain Injury Epidemiology Types of Traumatic Brain Injury Primary Injury Secondary Injury Treatment Cerebrovascular Disease and Stroke Epidemiology Ischemic Stroke Hemorrhagic Stroke Treatment Stroke Sequelae Cerebral Aneurysm and Arteriovenous Malformation Cerebral Aneurysms Arteriovenous Malformation Central Nervous System Infections Meningitis Encephalitis Brain Abscess 45 Chronic Disorders of Neurologic Function Brain and Cerebellar Disorders Spinal Cord and Peripheral Nerve Disorders 46 Alterations in Special Sensory Function Hearing and Balance Structure and Function of the Ear General Manifestations of Hearing Impairment Hearing Impairment Disorders Otitis Media Interventions for Individuals With Hearing Impairment Vision Structure of the Eye Visual Pathways General Manifestations of Visual Impairment Disorders of the Eye Interventions for Individuals With Vision Impairment Smell and Taste Disorders of Smell and Taste 47 Pain Physiology of Pain Types of Pain Acute Pain Chronic Pain Cancer-Related Pain Neuropathic Pain Ischemic Pain Referred Pain Physiologic Responses to Pain Pain in the Young and the Elderly Treatment Modalities Pharmacologic and Nonpharmacologic Pain Management UNIT XIII Neuropsychological Function 48 Mental Health Disorders Neurobiology of Psychiatric Disorders Common Psychiatric Disorders UNIT XIV Musculoskeletal Support and Movement 49 Structure and Function of the Musculoskeletal System Structure and Function of Bone Structure and Function of Joints Structure and Function of Articular Cartilage Structure and Function of Tendons and Ligaments Structure and Function of Skeletal Muscle Mechanics of Muscle Contraction 50 Alterations in Musculoskeletal Function Trauma Infection and Disease Soft Tissue Injuries Inert Soft Tissue Injuries Contractile Soft Tissue Injuries Bone Injuries and Infections Bone and Joint Trauma Infections of the Bone Alterations in Bone Structure and Mass Bone Structure Disorders Metabolic Bone Diseases Bone Tumors Diseases of Skeletal Muscle Idiopathic Inflammatory Myopathy Muscular Dystrophy Other Disorders of Muscle Myasthenia Gravis Chronic Muscle Pain 51 Alterations in Musculoskeletal Function Rheumatic Disorders Local Disorders of Joint Function Systemic Disorders of Joint Function Joint Dysfunction Secondary to Other Diseases Pediatric Joint Disorders UNIT XV Integumentary System 52 Alterations in the Integumentary System Age-Related Changes Evaluation of the Integumentary System Selected Skin Disorders Infectious Processes Inflammatory Conditions Allergic Skin Responses Parasitic Infestations Other Disorders of the Dermis Special Characteristics of Dark Skin Integumentary Manifestations of Systemic Disease Treatment Implications Developmental Considerations 53 Burn Injuries Thermal Injury Electrical Injury Chemical Injury Special Populations Index

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