Mitesh Dwivedi,
Mitesh Kumar Dwivedi,
DeLisa Fairweather
Elsevier Science
e druk, 2024
9780443139475
Regulatory T cells and Autoimmune Diseases
Specificaties
Paperback, blz.
|
Engels
Elsevier Science |
2024
ISBN13: 9780443139475
Rubricering
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Regulatory T Cells and Autoimmune Diseases addresses recent findings concerning the role of Tregs in the pathogenesis of autoimmune diseases as well as their therapeutic applications. In particular, this book deals with various Treg-based mechanisms that can lead to autoimmune disease and covers different aspects linking Tregs with autoimmune mechanisms involved in disease development by discussing animal models and human studies.
This book specifically focuses on Treg-based therapeutics and their targets to manage all known autoimmune rheumatic, central nervous system, bowel, liver, thyroid, kidney, myopathic, skin, blood and blood vessel, and eye diseases and aims to provide a must-have reference for designing therapeutic strategies to treat these autoimmune diseases. Additionally, this book covers vaccine-induced effects on the functioning of Tregs and development of CAR Treg therapy for autoimmune diseases and concludes with current challenges and future prospects of Treg-based therapeutics. This book is carefully designed to meet the requirements of both basic and advanced researchers in the area and provide new dimensions and insight into regulatory T cells’ role in autoimmune disease pathogenesis and therapy.
Specificaties
Inhoudsopgave
<p>Part I Regulatory T cells and immune system<br>1. Regulatory T cells and their functions in immune system<br>2. Regulatory T cells: mechanisms of action<br>3. Regulatory T cells and autoimmunity<br>4. Sex differences in regulatory T cells during autoimmune disease<br><br>Part II Role of regulatory T cells in rheumatic diseases<br>5. Role of regulatory T cells in pathogenesis and therapeutics of systemic lupus erythematosus<br>6. Role of regulatory T cells in the pathogenesis and therapeutics of primary Sjögren’s syndrome<br>7. Role of regulatory T cells in pathogenesis and therapeutics of rheumatoid arthritis and juvenile idiopathic arthritis<br>8. Role of regulatory T cells in pathogenesis and therapeutics of psoriatic arthritis<br>9. Role of regulatory T cells in pathogenesis and therapeutics of spondyloarthritis<br>10. Role of regulatory T cells in pathogenesis and therapeutics of ankylosing spondylitis<br><br>Part III Role of regulatory T cells in central nervous system demyelinating autoimmune diseases<br>11. Role of regulatory T cells in pathogenesis and therapeutics of multiple sclerosis<br>12. Role of regulatory T cells in the pathogenesis and therapeutics of neuromyelitis optica spectrum disorder<br><br>Part IV Role of regulatory T cells in peripheral nerve, muscle and neuromuscular autoimmune diseases<br>13. Role of regulatory T cells in pathogenesis and therapeutics of myasthenia gravis<br>14. Role of regulatory T cells in pathogenesis and therapeutics of GuillainBarré syndrome and experimental autoimmune neuritis<br>15. Role of regulatory T cells in pathogenesis and therapeutics of chronic inflammatory demyelinating polyradiculoneuropathy<br>16. Role of regulatory T cells in pathogenesis and therapeutics of dermatomyositis and polymyositis<br><br>Part V Role of regulatory T cells in inflammatory bowel diseases<br>17. Role of regulatory T cells in pathogenesis and therapeutics of Crohn’s disease and ulcerative colitis<br>18. Role of regulatory T cells in pathogenesis and therapeutics of celiac disease<br><br>Part VI Role of regulatory T cells in autoimmune liver diseases<br>19. Role of regulatory T cells in the pathogenesis and therapeutics of autoimmune hepatitis<br>20. Role of regulatory T cells in pathogenesis and therapeutics of primary biliary cholangitis and primary sclerosing cholangitis<br><br>Part VII Role of regulatory T cells in autoimmune thyroid diseases<br>21. Role of regulatory T cells in pathogenesis and therapeutics of Hashimoto’s thyroiditis<br>22. Role of regulatory T cells in pathogenesis and therapeutics of Graves’ disease and Graves’ orbitopathy<br><br>Part VIII Role of regulatory T cells in autoimmune lung and kidney diseases<br>23. Role of regulatory T cells in pathogenesis and therapeutics of Goodpasture’s syndrome (anti-glomerular basement membrane disease)<br>24. Role of regulatory T cells in pathogenesis and therapeutics of autoimmune glomerulonephritis (IgA vasculitis and IgA nephropathy)<br><br>Part IX Role of regulatory T cells in autoimmune skin diseases<br>25. Role of regulatory T cells in pathogenesis and therapeutics of vitiligo<br>26. Role of regulatory T cells in pathogenesis and therapeutics of psoriasis<br>27. Role of regulatory T cells in pathogenesis and therapeutics of atopic dermatitis<br>28. Role of regulatory T cells in pathogenesis and therapeutics of alopecia areata<br>29. Role of regulatory T cells in pathogenesis and therapeutics of pemphigus vulgaris and bullous pemphigoid<br>30. Role of regulatory T cells in pathogenesis and therapeutics of scleroderma (systemic sclerosis)<br><br>Part X Role of regulatory T cells in autoimmune blood and blood vessel disorders<br>31. Role of regulatory T cells in pathogenesis and therapeutics of primary antiphospholipid syndrome (Hughes syndrome)<br>32. Role of regulatory T cells in pathogenesis and therapeutics of Kawasaki disease<br>33. Role of regulatory T cells in pathogenesis and therapeutics of Behçet disease<br>34. Role of regulatory T cells in pathogenesis and therapeutics of immune thrombocytopenia<br>35. Role of regulatory T cells in pathogenesis and treatment of antineutrophil cytoplasmic antibody-associated vasculitis<br>36. Role of regulatory T cells in pathogenesis and therapeutics of autoimmune hemolytic anemia<br><br>Part XI Role of regulatory T cells in autoimmune eye diseases and type 1 diabetes mellitus<br>37. Role of regulatory T cells in pathogenesis and therapeutics of autoimmune uveitis<br>38. Role of regulatory T cells in pathogenesis and therapeutics of autoimmune retinopathy<br>39. Role of regulatory T cell in pathogenesis and therapeutics of type 1 diabetes mellitus<br><br>Part XII Current challenges and future prospects in research towards regulatory T cells based therapeutics in autoimmune diseases<br>40. Vaccines induced effects on functioning of regulatory T cells: autoimmune perspective<br>41. Probiotic interventions for regulatory T cells’ induction in autoimmune diseases<br>42. CAR Treg-based therapeutics for autoimmune diseases<br>43. Current challenges and future prospects of regulatory T cells based therapeutics in autoimmune disease</p>