Senescence, Senotherapeutics and Mitochondria

Specificaties
Gebonden, blz. | Engels
Elsevier Science | 2023
ISBN13: 9780443188862
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Elsevier Science e druk, 2023 9780443188862
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Senescence, Senotherapeutics and Mitochondria, Volume 136 offers updates on this unique topics, with chapters covering Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions, Mitochondria-associated Cellular Senescence Mechanisms: Biochemical and Pharmacological Perspectives, Mitochondria in cell senescence: Friend or Foe?, The role of mitochondria and mitophagy in cell senescence, Small molecules targeting mitochondrial dysfunction for potential senotheraputics, Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction, Mitochondrial targeting peptides and probes, Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases, and much more.

Other sections cover Targeting of mitostasis-proteostasis axis by antioxidant polysaccharides in neurodegeneration, Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders, Melatonin as mitochondria-targeted drugs, Coenzyme Q-related compounds to maintain healthy mitochondria during aging, Changing ROS, NAD and AMP: a path to longevity via mitochondrial therapeutics, and more.

Specificaties

ISBN13:9780443188862
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

1. Cellular Senescence in Aging: Molecular Basis, Implications and Therapeutic Interventions <p>Jemima Princilly, Bhavana Veerabhadrappa, Nagashree N. Rao and Madhu Dyavaiah</p> <p>2. Mitochondria in cell senescence: A Friend or Foe?</p> <p>Qian Chen, Lindon Young, Robert Barsotti</p> <p>3. The role of mitochondria and mitophagy in cell senescence</p> <p>Tayyab Ali, Fatma Hussain, Haroon Ur Rashid Kayani, Muhammad Naeem, and Fozia Anjum</p> <p>4. Mitochondria-associated cellular senescence mechanisms: Biochemical and pharmacological perspectives </p> <p>Mehmet Can Atayik and Ufuk Çakatay</p> <p>5. Changing ROS, NAD and AMP: A path to longevity via mitochondrial therapeutics</p> <p>Oleh Lushchak, Dmytro Gospodaryov, Olha Strilbytska, and Maria Bayliak</p> <p>6. Mitochondria-derived peptides in healthy ageing and therapy of age-related diseases</p> <p>Siarhei A. Dabravolski</p> <p>7. Senolytic and senomorphic interventions to defy senescence-associated mitochondrial dysfunction</p> <p>Jan O. Nehlin</p> <p>8. Melatonin as mitochondria-targeted drug</p> <p>Sibel Suzen, Luciano Saso</p> <p>9. Coenzyme Q-related compounds to maintain healthy mitochondria during aging</p> <p>Guillermo López-Lluch</p> <p>10. Targeting mitochondrial dysfunction to salvage cellular senescence for managing neurodegeneration</p> <p>Komal Sharma, Joyobrata Sarkar, Anchal Trisal, Rishika Ghosh, Anubhuti Dixit, Abhishek Kumar Singh</p> <p>11. Targeting the microbiota-mitochondria crosstalk in neurodegeneration with senotherapeutics</p> <p>Jan Homolak</p> <p>12. Therapeutic targeting of mitochondria–proteostasis axis by antioxidant polysaccharides in neurodegeneration</p> <p>Qiangqiang Wang, Muhammad Zeeshan Adil, Xiaoliang Xie, Shihao Zhao, Ju Zhang, and Zebo Huang</p> <p>13. Phytotherapeutic targeting of the mitochondria in neurodegenerative disorders</p> <p>Priyanka Sarkar, Ashish Kumar, Partha Sarathi Behera, and Kavitha Thirumurugan</p>
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        Senescence, Senotherapeutics and Mitochondria