Protein Structure Prediction and Analysis

Specificaties
Gebonden, blz. | Engels
Elsevier Science | 2025
ISBN13: 9780443294129
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Elsevier Science e druk, 2025 9780443294129
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Protein Structure Prediction and Analysis, Volume 146 offers a comprehensive exploration of the methodologies, tools, and techniques utilized in the prediction and analysis of protein structures. The book delves into the fundamental principles of protein folding, modeling, and computational simulations, providing insights into the intricate process of predicting the three-dimensional structures of proteins. Sections in this new release include coverage of Current approaches for protein structure prediction and design, Protein Modelling, Prediction servers and applications in molecular modelling, Toward accurate in silico prediction of antigen binding affinities in antibody engineering, Molecular Blueprints: Guiding Drug Discovery through Protein Structure Analysis, and much more.

Additional sections focus on Protein Structure Prediction Using Dynamic Speciation Evolutionary Algorithm with Problem Information Aggregation, Tau protein structure and dynamics, Tau interacts with G-protein coupled receptors (GPCRs), How to accurately predict nanobody structure: Classical physics-based simulations or deep learning approaches, Medicinal Chemistry-based Novel Therapeutics for Tauopathies in Alzheimer’s Disease, Mapping the Pathogenic Nexus: Gene Overlap and Protein Interaction Networks in Alzheimer's and Breast Cancer as a Precursor to Protein Structure Prediction and Analysis, and much more.

Specificaties

ISBN13:9780443294129
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

1. Current approaches for protein structure prediction and design<br>George Priya Doss Priya Doss C<br>2. Protein Modelling, Prediction servers and applications in molecular modelling<br>Selvaraj Chandrabose Sr.<br>3. Toward accurate in silico prediction of antigen binding affinities in antibody engineering<br>Seyit Kale, Sibel Kalyoncu Uzunlar, Hatice Döşeme, Merve Arslan and Tuğçe Uluçay<br>4. Molecular Blueprints: Guiding Drug Discovery through Protein Structure Analysis<br>Dileep Francis<br>5. Protein Structure Prediction Using Dynamic Speciation Evolutionary Algorithm with Problem Information Aggregation<br>Rafael Stubs Parpinelli Sr.<br>6. Tau protein structure and dynamics<br>Subashchandrabose Chinnathambi, Gowshika Velmurugan and Madhura Chandrashekar<br>7. Tau interacts with G-protein coupled receptors (GPCRs)<br>Subashchandrabose Chinnathambi, Madhura Chandrashekar, Gowshika Velmurugan, Vaishnavi Ananthanaraya and Nagaraj Rangappa<br>8. How to accurately predict nanobody structure: Classical physics-based simulations or deep learning approaches<br>Weiwei Xue<br>9. Medicinal Chemistry-based Novel Therapeutics for Tauopathies in Alzheimer&rsquo;s Disease<br>Subashchandrabose Chinnathambi, Sneha Malik, Madhura Chandrashekar and Murugappan Kumurappan<br>10. Mapping the Pathogenic Nexus: Gene Overlap and Protein Interaction Networks in Alzheimer's and Breast Cancer as a Precursor to Protein Structure Prediction and Analysis<br>Vinoth Kumar Raja<br>11. Predicting protein structural insight changes upon hotspot mutations of ERBB2 gene affecting NSCLC<br>George Priya Doss Priya Doss C<br>12. Computational Modeling of RET Hotspot Mutations in the NSCLC: Impact on Protein Structure, Dynamics, and Stability<br>George Priya Doss Priya Doss C<br>13. Deciphering the Impact of Genetic Variants of Unknown Significance in Inherited Retinal Disease Through Computational and Functional Approaches<br>Esther E. Biswas-Fiss, Senem Cevik, Jazzlyn Jones and Subhasis Biswas<br>14. The structure-based approaches to computing viral fitness<br>Rukmankesh Mehra and Shivani Thakur<br>15. Structural Insights from Neuraminidase Diversity: Implications for Selectivity in Anti-Infective and Anticancer Strategies<br>Ciro Leonardo Pierri<br>16. Machine learning and molecular modeling based design of nanobodies targeting human serotonin transporter and receptor<br>Weiwei Xue and Binbin Xu<br>17. Tau proteostasis in Alzheimer&rsquo;s Disease<br>Subashchandrabose Chinnathambi<br>18. SUMO inhibits Tau aggregation in Alzheimer's disease<br>Subashchandrabose Chinnathambi and Nagaraj Rangappa<br>19. Apolipoprotein E and Tau Interaction in Alzheimer's disease<br>Subashchandrabose Chinnathambi, Anusree Adithyan, Madhura Chandrashekar and Hariharakrishnan Chidambaram<br>20. Cholesterol metabolism regulates Tauopathy in Alzheimer's disease<br>Subashchandrabose Chinnathambi, Anusree Adithyan and Madhura Chandrashekar
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        Protein Structure Prediction and Analysis