A. K. Andrianov
John Wiley & Sons
e druk, 2009
9780470193433
Polyphosphazenes for Biomedical Applications
Specificaties
Gebonden, 480 blz.
|
Engels
John Wiley & Sons |
2009
ISBN13: 9780470193433
Rubricering
Verwachte levertijd ongeveer 16 werkdagen
Samenvatting
This book serves as both an introduction and a practical guide on the synthesis and use of polyphosphazenes, a new and very versatile polymer family which has recently demonstrated bioactivity, biocompatibility, and biodegradability. These polymers find uses as potent vaccine adjuvants and microencapsulating agents; biodegradable materials and scaffolds for tissue engineering; biocompatible coatings and carriers for gene delivery, for example. A broad spectrum of application specialists working in chemistry, life scientists, and chemical engineering will appreciate this single–source reference.
Specificaties
Inhoudsopgave
CONTRIBUTORS.
<p>PREFACE.</p>
<p>I INTRODUCTION.</p>
<p>1 Polymers for Biology and Medicine – Current Status and Future Prospects (Alexander K. Andrianov and Robert Langer).</p>
<p>2 Expanding Options in Polyphosphazene Biomedical Research (Harry R. Allcock).</p>
<p>II VACCINE DELIVERY AND IMMUNOMODULATION.</p>
<p>3 Polyphosphazenes as Vaccine Delivery Systems (Alexander K. Andrianov).</p>
<p>4 The Potential of Polyphosphazenes in Modulating Vaccine–Induced Immune Responses I: Investigations In Mice (George Mutwiri, Ponn Benjamin, Alexander K. Andrianov, and Lorne Babiuk).</p>
<p>5 The Potential of Polyphosphazenes in Modulating Vaccine–Induced Immune Responses II: Investigations In Large Animals (George Mutwiri and Lorne Babiuk).</p>
<p>6 Polyphosphazenes as Adjuvants for Inactivated and Subunit Rotavirus Vaccines in Adult and Infant Mice (Kari Johansen, Jorma Hinkula, Claudia Istrate, Elin Johansson, Didier Poncet, and Lennart Svensson).</p>
<p>7 Polyphosphazene Immunoadjuvants for Intradermal Vaccine Delivery (Alexander K. Andrianov, Daniel P. DeCollibus, Helice A. Gillis, Henry H. Kha, Alexander Marin).</p>
<p>III BIOMATERIALS.</p>
<p>8 Biodegradable Polyphosphazene Scaffolds for Tissue Engineering (Syam P. Nukavarapu, Sangamesh G. Kumbar, Harry R. Allcock and Cato T. Laurencin).</p>
<p>9 Biodegradable Polyphosphazene Blends for Biomedical Applications (Meng Deng, Lakshmi S. Nair, Nicholas R. Krogman, Harry R. Allcock, Cato T. Laurencin).</p>
<p>10 Polyphosphazenes from Condensation Polymerization (Patty Wisian–Neilson).</p>
<p>11 Electrospun Polyphosphazene Nanofibers For In Vitro Osteoblast Culture (Maria Teresa Conconi, Paolo Carampin, Silvano Lora, Claudio Grandi, Pier Paolo Parnigotto).</p>
<p>12 Phosphazenes and Surfaces (Mario Gleria, Roberto Milani, Roberta Bertani, Angelo Boscolo Boscoletto, and Roger De Jaeger).</p>
<p>IV DRUG DELIVERY SYSTEMS.</p>
<p>13 Amphiphilic Ionizable Polyphosphazenes for the Preparation of pH–Responsive Liposomes (David Ghattas and Jean–Christophe Leroux).</p>
<p>14 Poly– and Cyclophosphazenes as Drug Carriers for Anticancer Therapy (Youn Soo Sohn and Yong Joo Jun).</p>
<p>15 Amphiphilic Polyphosphazenes as Drug Carriers (Liyan Qiu and Cheng Zheng).</p>
<p>16 Synthesis and Characterization of Organometallic Derivatives of Polyphosphazenes and their Applications in Nanoscience (Carlos Diaz and M. L. Valenzuela).</p>
<p>17 Transport Properties of Polyphosphazenes (Joel R. Fried).</p>
<p>V BIODETECTION.</p>
<p>18 Potentiometric Monitoring Antibody–Antigen Interactions by and Stabilization of Polyanilineand Electrodes with p–Sulfonated Poly(bisphenoxyphosphazene) (Byeongyeol Kim, Alexander K. Andrianov, Alok Prabhu, Vladimir Sergeyev, and Kalle Levon).</p>
<p>VI WELL–DEFINED POLYPHOSPHAZENES: SYNTHETIC ASPECTS AND NOVEL MOLECULAR ARCHITECTURES.</p>
<p>19 Synthesis and chemical regularity in phosphazene copolymers (Gabino A. Carriedo).</p>
<p>20 Supramolecular Structures of Cyclophosphazenes(Alexander Steiner</p>
<p>APPENDIX A.</p>
<p>INDEX. </p>
<p>PREFACE.</p>
<p>I INTRODUCTION.</p>
<p>1 Polymers for Biology and Medicine – Current Status and Future Prospects (Alexander K. Andrianov and Robert Langer).</p>
<p>2 Expanding Options in Polyphosphazene Biomedical Research (Harry R. Allcock).</p>
<p>II VACCINE DELIVERY AND IMMUNOMODULATION.</p>
<p>3 Polyphosphazenes as Vaccine Delivery Systems (Alexander K. Andrianov).</p>
<p>4 The Potential of Polyphosphazenes in Modulating Vaccine–Induced Immune Responses I: Investigations In Mice (George Mutwiri, Ponn Benjamin, Alexander K. Andrianov, and Lorne Babiuk).</p>
<p>5 The Potential of Polyphosphazenes in Modulating Vaccine–Induced Immune Responses II: Investigations In Large Animals (George Mutwiri and Lorne Babiuk).</p>
<p>6 Polyphosphazenes as Adjuvants for Inactivated and Subunit Rotavirus Vaccines in Adult and Infant Mice (Kari Johansen, Jorma Hinkula, Claudia Istrate, Elin Johansson, Didier Poncet, and Lennart Svensson).</p>
<p>7 Polyphosphazene Immunoadjuvants for Intradermal Vaccine Delivery (Alexander K. Andrianov, Daniel P. DeCollibus, Helice A. Gillis, Henry H. Kha, Alexander Marin).</p>
<p>III BIOMATERIALS.</p>
<p>8 Biodegradable Polyphosphazene Scaffolds for Tissue Engineering (Syam P. Nukavarapu, Sangamesh G. Kumbar, Harry R. Allcock and Cato T. Laurencin).</p>
<p>9 Biodegradable Polyphosphazene Blends for Biomedical Applications (Meng Deng, Lakshmi S. Nair, Nicholas R. Krogman, Harry R. Allcock, Cato T. Laurencin).</p>
<p>10 Polyphosphazenes from Condensation Polymerization (Patty Wisian–Neilson).</p>
<p>11 Electrospun Polyphosphazene Nanofibers For In Vitro Osteoblast Culture (Maria Teresa Conconi, Paolo Carampin, Silvano Lora, Claudio Grandi, Pier Paolo Parnigotto).</p>
<p>12 Phosphazenes and Surfaces (Mario Gleria, Roberto Milani, Roberta Bertani, Angelo Boscolo Boscoletto, and Roger De Jaeger).</p>
<p>IV DRUG DELIVERY SYSTEMS.</p>
<p>13 Amphiphilic Ionizable Polyphosphazenes for the Preparation of pH–Responsive Liposomes (David Ghattas and Jean–Christophe Leroux).</p>
<p>14 Poly– and Cyclophosphazenes as Drug Carriers for Anticancer Therapy (Youn Soo Sohn and Yong Joo Jun).</p>
<p>15 Amphiphilic Polyphosphazenes as Drug Carriers (Liyan Qiu and Cheng Zheng).</p>
<p>16 Synthesis and Characterization of Organometallic Derivatives of Polyphosphazenes and their Applications in Nanoscience (Carlos Diaz and M. L. Valenzuela).</p>
<p>17 Transport Properties of Polyphosphazenes (Joel R. Fried).</p>
<p>V BIODETECTION.</p>
<p>18 Potentiometric Monitoring Antibody–Antigen Interactions by and Stabilization of Polyanilineand Electrodes with p–Sulfonated Poly(bisphenoxyphosphazene) (Byeongyeol Kim, Alexander K. Andrianov, Alok Prabhu, Vladimir Sergeyev, and Kalle Levon).</p>
<p>VI WELL–DEFINED POLYPHOSPHAZENES: SYNTHETIC ASPECTS AND NOVEL MOLECULAR ARCHITECTURES.</p>
<p>19 Synthesis and chemical regularity in phosphazene copolymers (Gabino A. Carriedo).</p>
<p>20 Supramolecular Structures of Cyclophosphazenes(Alexander Steiner</p>
<p>APPENDIX A.</p>
<p>INDEX. </p>