Contributors; Preface; Part I. Historical Perspective: 1. Neuroleptic-induced movement disorders: historical perspective Marc-Alain Wolf, Ramzy Yassa and Pierre-Michel Llorca; Part II. Clinical Aspects of Tardive Dyskinesia: 2. Aging and tardive dyskinesia Bruce L. Saltz, John M. Kane, Margaret G. Woerner, Jeffrey A. Lieberman and José Ma. J. Alvir; 3. Gender as a factor in the development of tardive dyskinesia Ramzy Yassa and Dilip V. Jeste; 4. The Yale tardive dyskinesia study: a prospective incidence study among long-term outpatients William M. Glazer, Hal Morgenstern, Donna Raye Wagner and John Doucette; 5. Vulnerability to tardive dyskinesia in schizophrenia: an exploration of individual patient factors John L. Waddington, Eadbhard O'Callaghan, Peter Buckely, Cathy Madigan, Conall Larkin and Anthony Kinsella; 6. Tardive dyskinesia and affective disorder George Gardos and Jonathan O. Cole; 7. Diabetes mellitus and tardive dyskinesia Sukdeb Mukherjee and Sahebarao P. Mahadik; 8. Other factors in the development of tardive dyskinesia Ramzy Yassa; 9. Neuroleptic treatment and tardive dyskinesia George Gardos and Jonathan O. Cole; 10. Anticholinergic drugs as factors in the development of tardive dyskinesia Ramzy Yassa and N. P. V. Nair; Part III. Mechanisms Underlying Tardive Dyskinesia: 11. Neurochemistry of the basal ganglia N. P. V. Nair and T. E. G. West; 12. A reanalysis of the dopamine theory of tardive dyskinesia: the hypothesis of dopamine D1/D2 imbalance Linda Peacock and Jes Gerlach; 13. Tardive dyskinesia and phenylalanine metabolism: risk-factor studies Mary Ann Richardson, Cheryl Flynn, Laura Read, Margaret Reilly and Raymond Suckow; 14. Neuroendocrinological studies of tardive dyskinesia Margot Albus; 15. Cognitive deficits and tardive dyskinesia Marion E. Wolf, Alan S. DeWolfe and Aron D. Mosnaim; 16. Studies of tardive dyskinesia using computed tomography and magnetic-resonance imaging Christian L. Shriqui; 17. Rodent and other animal models of tardive dyskinesia during long-term neuroleptic-drug administration: controversies and implications for the clinical syndrome John L. Waddington; Part IV. Measurement of Tardive Dyskinesia: 18. Instrument measurements of tardive dyskinesia Michael P. Caligiuri; Part V. Tardive Dyskinesia in Different Populations: 19. Cultural aspects of tardive dyskinesia in Asia Shigeto Yamawaki, Teruo Hayashi; Ikuo Nagaoka, Hiroshi Saitoh, Norio Yokota and Yosuke Uchitomi; 20. Tardive dyskinesia in North America and the Middle East Driss Moussaoui; 21. Tardive dyskinesia in Europe H. A. McClelland and T. A. Kerr; 22. Role of ethnicity in the development of tardive dyskinesia Jonathan P. Lacro and Dilip V. Jeste; 23. Tardive dyskinesia in children and adolescents Mark Magulac and Dilip V. Jeste; Part VI. Other Neuropleptic-Induced Movement Disorders: 24. Drug-induced parkinsonism Thomas E. Hansen and William F. Hoffman; 25. Clinical aspects of neuroleptic-induced dystonia George A. Keepers and Linda Ganzini; 26. Tardive dystonia Paul Greene; 27. Tardive akathisia Robert E. Burke; Part VII. Treatment of Tardive Dyskinesia: 28. Development of novel antipsychotic drugs with reduced extrapyramidal side effects Allan Z. Safferman, Jeffrey A. Lieberman, Bruce J. Kinon, Daniel Umbricht, Jeffrey S. Aronowitz and John M. Kane; 29. GABAergic treatments for tardive dyskinesia Shawn L. Cassady, Gunvant K. Thaker and Carol A. Tamminga; 30. Using biofeedback to train suppression of the oral-lingual movements of tardive dyskinesia Ronald C. Fudge and Cecile E. Sison; Index.