1. Introduction Tracey J. Woodruff and Linda C. Giudice; 2. Environmental contaminants and exposure Mary A. Fox and Yutaka Aoki; 3. Development and maturation of the normal female reproductive system: 3.1. Ovary Laxmi A. Kondapalli and Teresa K. Woodruff; 3.2. Oviduct and uterus Leo F. Doherty and Hugh S. Taylor; 3.3. Breast Maricel V. Maffini, Carlos Sonnenschein and Ana M. Soto; 4. Development and maturation of the normal male reproductive system Richard M. Sharpe; 5. Modern genetics of reproductive biology Taisen Iguchi and Tamotsu Sudo; 6. Mechanisms of endocrine disruption K. Leigh Greathouse and Cheryl L. Walker; 7. Developmental exposures and implications for early and latent disease Retha R. Newbold and Jerrold J. Heindel; 8. Wildlife as sentinels of environmental impacts on reproductive health and fertility Heather J. Hamlin and Louis J. Guillette Jr; 9. Environmental contaminants and effects on timing and progression of human pubertal development Annette Mouritsen, Julie Damm, Lise Aksglaede, Kaspar Sørensen and Anders Juul; 10. Environmental contaminants and impacts on healthy and successful pregnancies Rémy Slama and Sylvaine Cordier; 11. Environmental contaminants and the reproductive and fertility effects in the male: 11.1. Introduction Sarah J. Janssen; 11.2. Environmental contaminants and male reproductive health: possible role of fetal exposure Jorma Toppari, Helena E. Virtanen and Niels E. Skakkebaek; 11.3. Environmental contaminants and male reproductive health: adult exposure and effects on fertility John D. Meeker and Russ Hauser; 12. Environmental contaminants, female reproductive health and fertility Pauline Mendola and Germaine M. Buck Louis; 13. Environmental contaminants and related systems that have implications for reproduction: 13.1. The neuroendocrine system Andrea C. Gore; 13.2. The thyroid system R. Thomas Zoeller and John D. Meeker; 13.3. The immune system Robert W. Luebke and Dori R. Germolec; 14. Environmental contaminants and cancers of the reproductive tract Gail S. Prins and Esther L. Calderon; 15. Communicating with patients and the public about environmental exposures and reproductive risk Gina M. Solomon and Sarah J. Janssen; 16. Interpreting science in the policy context Tracey J. Woodruff and Sarah J. Janssen; 17. Conclusions – what does all this mean and where are we going? Shanna H. Swan, Patricia Hunt and Linda C. Giudice; Index.