Nitric Oxide in Health and Disease

Part I. Basic Principles and Recent Advances: 1. Nitric oxide: introduction and historical background; 2. Synthesis and properties of nitric oxide; 3. Endothelium-derived nitric oxide; 4. Nitric oxide in the central nervous system; 5. Nitric oxide in the peripheral nervous system; 6. Nitric oxide in the immune system; Part II. Pathological Implications of Nitric Oxide: Introduction; 7. Type II NOS and immune inflammatory disorders; 8. Type III NOS and cardiovascular disease; 9. Type I NOS and disorders of the central and peripheral nervous systems; Summary; Part III. Experimental Approaches: 10. Biochemistry and molecular biology; 11. Pharmacology; 12. Microscopy; Part IV. Protocols and Techniques: 13. Measurement of nitric oxide; 14. Measurement of nitric oxide synthase activity; 15. Pharmacology; 16. Microscopy; Appendix I. Distribution of constitutive nitrogen oxide synthase in animal organs/tissues; Appendix II. Peripheral tissues and organs in which nitric oxide has been identified as a neurotransmitter; References.