Annual Review Prize Lectures: Elementary and global aspects of calcium signalling M. J. Berridge; Voltage-gated and inwardly rectifying potassium channels L. Y. Jan, Y. N. Jan; Topical Reviews: Mechanisms of modulation of voltage-dependent calcium channels by G proteins A. C. Dolphin; Structure and function of voltage-gated sodium channels E. Marban, T. Yamagishi, G. F. Tomaselli; Rhythmicity, synchronization and binding in human and primate motor systems S. F. Farmer; Hypoxia and smooth muscle function: key regulatory events during metabolic stress M. J. Taggart, S. Wray; Colour processing in the primate retina: recent progress P. R. Martin; Perspectives: The paradox of hair cell adaptation C. J. Kros; Two forms of triggered endocytosis in regulated secretory cells R. D. Burgoyne; Bayliss, myogenic tone and volume-regulated chloride channels in arterial smooth muscle M. T. Nelson; Which Ca2+ channels control cardiac E-C coupling? P. Lipp, M. D. Bootman; Ca2+-induced Ca2+ release: physiological experiments on a new level W. G. Wier; Synchronisation of somato-sympathetic outflows during exercise: role for a spinal rhythm generator J. T. Potts, J. H. Mitchell; Direct and indirect regulation of a single ion channel N. S. Magoski, L. K. Kaczmarek; The revival of the role of the mitochondrion in regulation of transmitter release N. Melamed-Book, R. Rahamimoff; Learning to cope with repeated stress G. Leng, J. A. Russell; K+-Cl- cotransport: 'to be or not to be' oxygen sensitive P. K. Lauf; The J reflex J. G. Widdicombe; A short-term mechanism of plasticity for interneurones? C. J. McBain; Ion channel activity drives ion channel expression A. B. Ribera; Muscle geometry R. McNeill Alexander; The generation of directionally selective responses in the retina S. C. Mangel; Another trigger for the heartbeat A. W. Trafford, D. A. Eisner; The continuing debate about CNS control of proprioception A. Prochazka, M. Hulliger; Cross-talk between apparently independent receptors T. J. Searl, E. M. Silinsky.