Doing Research in Emergency and Acute Care – Making Order Out of Chaos
Making Order Out of Chaos
Samenvatting
A practical guide to understanding and navigating the unique challenges faced by physicians and other professionals who wish to undertake research in the ED or other acute care setting.
Focusing on the hyper–acute and acute care environment and fulfilling two closely–related needs:
1) the need for even seasoned researchers to understand the specific logistics and issues of doing research in the ED; and 2) the need to educate clinically active physicians in research methodology.
This new text is not designed to be a complex, encyclopedic resource, but instead a concise, easy–to–read resource designed to convey key need–to–know information within a comprehensive framework. Aimed at the busy brain, either as a sit–down read or as a selectively–read reference guide to fill in knowledge gaps, chapters are short, compartmentalized, and are used strategically throughout the text in order to introduce and frame concepts. This format makes it easy – and even entertaining – for the research novice to integrate and absorb completely new (and typically dry) material.
The textbook addresses aspects of feasibility, efficiency, ethics, statistics, safety, logistics, and collaboration in acute research. Overall, it grants access for the seasoned researcher seeking to learn about acute research to empathically integrate learning points into his or her knowledge base.
As the ED is the primary setting for hyper–acute and acute care, and therefore a prime site for related clinical trial recruitment and interventions, the book presents specific logistical research challenges that researchers from any discipline, including physicians, research nurse coordinators, study monitors, or industry partners, need to understand in order to succeed.
Specificaties
Inhoudsopgave
<p>Part 1: Getting ready: Preparing for your research study</p>
<p>1 Aspects of research specific to acute care, 3<br />Jarrod M. Mosier and Peter Rosen</p>
<p>2 Aspects of feasibility in research, 7<br />Kama Z. Guluma</p>
<p>3 How do I formulate a research question?, 13<br />Michael P. Wilson</p>
<p>4 Evidence ]based medicine: Finding the knowledge gap, 17<br />Eddy Lang and Zubair Bayat</p>
<p>5 How to carry out an efficient literature search, 21<br />Aleksandr Tichter, Louise Falzon, and Peter Wyer</p>
<p>6 What do I need to know to get started with animal and basic science research?, 31<br />George J. Shaw</p>
<p>7 The IRB process: How to write up a human studies protocol, 37<br />Christian Tomaszewski</p>
<p>8 Ethics in research: How to collect data ethically, 45<br />Nas Rafi and Brian Snyder</p>
<p>9 Safety in research: How to ensure patient safety?, 53<br />Robert Grover and Vicken Y. Totten</p>
<p>Part 2: Getting it done: Doing your research study</p>
<p>10 How to design a study that everyone will believe: Minimizing bias and confounding, 61<br />Michael Witting</p>
<p>11 How to design a study that everyone will believe: An overview of research studies and picking the right design, 65<br />Julian Villar, Jennifer Lanning, and Robert Rodriguez</p>
<p>12 How to design a study that everyone will believe: Random selection and allocation of patients to treatment conditions, 71<br />Katie L. Tataris, Mary Mercer, and Prasanthi Govindarajan</p>
<p>13 How to design a study that everyone will believe: Surveys, 79<br />Edward M. Castillo and Gary M. Vilke</p>
<p>14 How to design a study that everyone will believe: Retrospective reviews, 85<br />Jonathan Auten and Paul Ishimine</p>
<p>15 How to design a study that everyone will believe: Prehospital studies, 93<br />Christopher Kahn</p>
<p>16 How to design a study that everyone will believe: Ethical concepts for special populations in emergency research, 97<br />Kimberly Nordstrom</p>
<p>17 How to design a study that everyone will believe: Industry studies, 105<br />Richard F. Clark and Alicia B. Minns</p>
<p>18 How to design a study that everyone will believe: Prospective studies, 115<br />Gary Gaddis</p>
<p>19 How to design a study that everyone will believe: effectiveness, safety, and the intention to treat, 121<br />Ashleigh Campillo, Christopher J. Coyne, and Juan A. Luna</p>
<p>20 How to design a study that everyone will believe: Emergency department operations and systems, 129<br />Vaishal Tolia</p>
<p>21 How to design a study that everyone will believe: The challenges of doing international research, 133<br />Vicken Y. Totten</p>
<p>22 The development of clinical prediction rules, 139<br />Benton R. Hunter and Christopher R. Carpenter</p>
<p>23 Testing the safety and efficacy of devices: Device safety, as well as obtaining an IDE (investigational device exemption) from the FDA, 149<br />Sean ]Xavier Neath</p>
<p>24 Privacy in research: How to collect data safely and confidentially, 155<br />Gary M. Vilke and Edward M. Castillo</p>
<p>25 How do I establish a research assistant program?, 161<br />Judd E. Hollander</p>
<p>26 How to complete a research study well and in a minimum of time: The importance of collaboration, 167<br />Austin Hopper and Michael P. Wilson</p>
<p>Part 3: Getting it out there: Analyzing and publishing your study</p>
<p>27 Eliminating common misconceptions to enable intelligent use of biostatistics: How can a novice use statistics more intelligently?, 175<br />Gary Gaddis</p>
<p>28 Basic statistics: sample size and power: How are sample size and power calculated?, 183<br />Manish Garg, Richard Harrigan, and Gary Gaddis</p>
<p>29 Basic statistics: Means, P values, and confidence intervals, 191<br />Daniel del Portal and Richard Harrigan</p>
<p>30 Basic statistics: Assessing the impact of therapeutic interventions with odds–ratios, relative risk, and hazard ratios, 199<br />Jesse J. Brennan and Edward M. Castillo</p>
<p>31 Basic statistics: Assessing the impact of a diagnostic test; choosing a gold standard, sensitivity, specificity, PPV, NPV, and likelihood ratios, 205<br />Stephen R. Hayden</p>
<p>32 Advanced biostatistics: Chi ]square, ANOVA, regression, and multiple regression, 213<br />Gary Gaddis</p>
<p>33 Can I combine the results of this study with others? An introduction to systematic reviews, 223<br />Brian H. Rowe</p>
<p>34 How to write a scientific paper for publication, 231<br />Stephen R. Hayden</p>
<p>35 How do I make reviewers happy? The review process: What do reviewers look for in a manuscript? What is the review process?, 239<br />David J. Karras and Jacob W. Ufberg</p>
<p>36 How do I write a grant?, 247<br />Zachary D.W. Dezman and Jon Mark Hirshon</p>
<p>37 How to make an academic career: Developing a successful path in research, 253<br />Deirdre Anglin and Michael Menchine</p>
<p>Glossary, 259</p>
<p>Index, 267</p>