1. Fifty years of transformation of acute and emergency care Benjamin Easter; 2. Measuring and improving quality of care Jesse M. Pines, Mark S. Zocchi, C. Noelle Dietrich and Molly Benoit; 3. Fragmentation in acute and emergency care: causes, consequences and solutions Benjamin Easter and Arjun Venkatesh; 4. Alternative payment models in acute, episodic care: moving from volume to value Nir J. Harish and Jesse M. Pines; 5. Improving timeliness and access of acute and emergency care: the science of improving emergency department crowding Olan A. Soremekun; 6. Bringing the patient-voice into emergency care Marc A. Probst and Erik P. Hess; Case study 1. Expanding the role of observation care Christopher W. Baugh, Christopher Caspers and Anthony M. Napoli; Case study 2. An innovative strategy to streamline care for behavioral health in the emergency department Michael Turturro, Leslie Zun and Jack Rozel; Case study 3. The geriatric emergency department Ula Hwang and Christopher R. Carpenter; Case study 4. How the UK responded to the 4-hour rule Suzanne Mason and Michael J. Schull; Case study 5. High-cost users: using information technology to streamline care plans Dawn Williamson and Jody A. Vogel; Case study 6. Emergency care in an integrated healthcare delivery system: the Kaiser experience Dana R. Sax, Jeffrey S. Selevan and Wm. Wesley Fields; Case study 7. Urgent care centers: an alternative to unscheduled primary care and emergency department care Judd E. Hollander and Jesse M. Pines; Case study 8. The 'no-wait' emergency department Chris McStay and Jody Crane; Case study 9. Transforming care delivery through telemedicine Judd E. Hollander and Brendan G. Carr; Case study 10. Coordinating emergency care through telemedicine Sarah A. Sterling, Kristi Henderson and Alan E. Jones; Case study 11. Bringing diagnostic testing to the bedside: point of care testing Benjamin Easter and Kelly Bookman; Case study 12. Regionalization of care M. Kit Delgado, Fred Lin and Brendan G. Carr; Case study 13. Clinical decision support tools Kelly Bookman and Ali S. Raja; Case study 14. Automated patient follow-up program Tom Scaletta, Kristin L. Rising and Megan Ranney; Case study 15. Using data on patient experience to improve clinical care Seth Glickman and Abhi Mehrotra; Case study 16. Community paramedicine: the Geisinger experience Manish N. Shah and David J. Schoenwetter; Case study 17. Initiating palliative care in the emergency department Christian Jacobus and Tammie E. Quest; Case study 18. Streamlining patient flow in the emergency department with discrete event simulation Eric J. Goldlust, T. Eugene Day and Nathan R. Hoot; Case study 19. Using emergency department community health workers as a bridge to ongoing care for frequent ED users Roberta Capp and Richard Zane; Case study 20. Big data: use of analytics for operations management Joe Guarisco and James Langabeer II.