R. Numerof,
Charles A. Dinarello,
Khusru Asadullah
Springer Berlin Heidelberg
e druk, 2014
9783642421822
Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases
Specificaties
Paperback, blz.
|
Engels
Springer Berlin Heidelberg |
2014
ISBN13: 9783642421822
Rubricering
Onderdeel van serie
Ernst Schering Foundation Symposium Proceedings
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Cytokines and cytokine receptors remain an area of great interest for the development of targeted therapies for cutaneous inflammatory diseases. Anti-TNF therapeutics have proven to be effective in the treatment of psoriasis, and clinical investigations have now begun for other cytokine-directed therapies, such as those targeting IFN-g, IL-12p40, and IL-18. In addition to therapeutics that target cytokines directly, strategies that target cytokine signaling pathways are in development. This book summarizes the findings of the 56th International Workshop of the Ernst Schering Research Foundation that focused on "Cytokines as Potential Therapeutic Targets for Inflammatory Skin Diseases".
Specificaties
ISBN13:9783642421822
Taal:Engels
Bindwijze:paperback
Uitgever:Springer Berlin Heidelberg
Inhoudsopgave
Inhibition of IFN-? as a Method of Treatment of Various Autoimmune Diseases, Including Skin Diseases.- Cytokine Targeting in Psoriasis and Psoriatic Arthritis: Beyond TNF?.- Inhibitors of Histone Deacetylases as Anti-inflammatory Drugs.- Dendritic Cell Interactions and Cytokine Production.- Lysosomal Cysteine Proteases and Antigen Presentation.- DCs and Cytokines Cooperate for the Induction of Tregs.- Induction of Immunity and Inflammation by Interleukin-12 Family Members.- The Role of TNF? and IL-17 in the Development of Excess IL-1 Signaling-Induced Inflammatory Diseases in IL-1 Receptor Antagonist-Deficient Mice.- TGF?-Mediated Immunoregulation.- TNF Blockade: An Inflammatory Issue.- IL-1 Family Members in Inflammatory Skin Disease.- Regulatory T Cells in Psoriasis.