Phosphoinositides in Subcellular Targeting and Enzyme Activation

Specificaties
Paperback, 209 blz. | Engels
Springer Berlin Heidelberg | 2012
ISBN13: 9783642622991
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Springer Berlin Heidelberg 0e druk, 2012 9783642622991
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Samenvatting

Cells of the immune system are activated by a variety of stimuli that are derived from other cells, ingested material or from invading microorganisms. This issue of CTMI focuses on the mechanisms of phosphoinositide-mediated protein recruitment to intracellular membranes.

Specificaties

ISBN13:9783642622991
Taal:Engels
Bindwijze:paperback
Aantal pagina's:209
Uitgever:Springer Berlin Heidelberg
Druk:0

Inhoudsopgave

Preface.- Phosphoinositide involvement in phagocytosis and phagosome maturation.- Regulation of endocytosis by phosphatidylinositol 4,5-biphosphate and ENTH proteins.- Membrane targeting by pleckstrin homology (PH) domains.- Protein targeting to endosomes and phagosomes via FYVE and PX domains.- Regulation of the actin cytoskeleton by PI(4,5)P2 and PI(3,4,5)P3.- Roles of PI3K in neutrophil function.- Nuclear phosphoinositides and their functions.- Subject index.
€ 120,99
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        Phosphoinositides in Subcellular Targeting and Enzyme Activation