Molecular Mechanisms of Hormone Action

1.- Mode of Action of Steroid Hormones: A Historical Review.- Interaction of Steroid Hormone Receptors with DNA.- Clustered Arrangement and Interaction of Steroid Hormone Receptors with Other Transcription Factors.- Chromatin Template Remodeling and Steroid Receptor Transactivation of MMTV.- Hormone-Dependent Transcriptional Activation by Thyroid Hormone Receptors: Functional Homology with Steroid Hormone Receptors.- Subunit Structure of the Glucocorticoid Receptor.- Modulation of Glucocorticoid Hormone Action by Oncogenes and Peptide Hormones.- Studies on the Regulation of Glycogen and Lipid Metabolism by Insulin and Growth Factors: The Involvement of Receptor Tyrosine Kinase Activation and Casein Kinase II.- 2.- Genes Coding for G Proteins in Mammalian and Yeast Cells.- The ras Oncogene Protein.- Molecular Mechanisms of G-Protein Activation.- Interaction of Transducin with Retinal cGMP Phosphodiesterase.- Phosphonositide Metabolism and Visual Signal Transduction.- Hormonal Regulation of Phospholipases.- 3.- Regulation of Ion Channels.- The Structure of the Skeletal and Nonskeletal Muscle Calcium Channel.- Involvement of Pertussis Toxin-Sensitive G-Proteins in the Modulation of Voltage-Dependent Ca2+ Channels by Extracellular Signals.- Multiple Roles of G Proteins in Coupling of Receptors to Ionic Channels and Other Effectors.- The Guanylate Cyclase Family.- Mechanisms for Hormonal Regulation of the Different Isoforms of Guanylate Cyclase.- Catecholamine Receptors: Structure, Function, and Regulation.