Preclinical Hyperthermia

Modification of Heat Action and Thermal Enhancement of Radio- and Chemotherapy.- Hyperthermic Toxicity and the Modulation of Heat Damage to Cell Protein Synthesis in HeLa Cells.- Membranes as Targets for Hyperthermic Cell Killing.- Sulfhydryl Compounds as Thermosensitizers.- Therapeutic Benefit from Combined Heat and Radiation.- Correlation Between Polymerase ? Activity and Thermal Radiosensitization in Chinese Hamster Ovary Cells.- Effect of Heat and Combined Treatments on Normal Tissues.- The Problem of Defining Thermal Dose.- Effect of Hyperthermia on Human Natural Killer Cells.- Effect of Hyperthermia at 40.5° C and Cytostatic Drugs on Human Bone Marrow Progenitor Cells.- Combined Heat and X-Ray Toxicities in Intestine and Skin.- Toxic Effects of Irradiation or Doxorubicin in Combination with Moderate Whole-Body Hyperthermia on Bone Marrow in Rats.- Cardiotoxicity of Moderate Whole-Body Hyperthermia, Doxorubicin, and Combined Treatment in Rats.- Predinical Hyperthermia in Animal Tumors and Malignant Cell Lines.- Effects of Hyperthermic Treatments on Malignant Cells and Animal Tumors: Introductory Remarks.- Hyperthermia and Microcirculatory Effects of Heat in Animal Tumors.- Importance of the Glutathione Level and the Activity of the Pentose Phosphate Pathway in Cellular Heat Sensitivity.- Potentiation of Hyperthermia by Lanthanum.- Interactions of Hyperthermia with Hypoxic Cell Sensitisers.- Thermal Enhancement of the Cell Killing Effect of X-Irradiation in Mammalian Cells in Vitro and in a Transplantable Mouse Tumor: Influence of pH, Thermotolerance, Hypoxia, or Misonidazole.- Thermal Enhancement of Drug Cytotoxicity in Vivo and in Vitro.- Effect of Heat and Combined Treatments on Human Tumors.- Preclinical Hyperthermia in Human Tumors: Introductory Remarks.- Microcirculatory and pH Alterations in Isotransplanted Rat and Xenotransplanted Human Tumors Associated with Hyperthermia.- Effects of Heat Treatment in Vitro and in Vivo on Human Melanoma Xenografts.- Intrinsic Thermosensitivity of Various Human Tumors.- Importance of Thermotolerance for Radiothermotherapy as Assessed Using Two Human Melanoma Cell Lines.- In Vitro Thermochemotherapy in Ovarian Cancer.- Effect of Hyperthermia at 40.5° C and Chemotherapy on Various Human Tumors in Vitro.- Predictive Assays for Tumor Response to Single and Multiple Fractions of Hyperthermia.- Predicting the Sensitivity of Human Cancers to Combined Chemotherapy and Hyperthermia.