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Clusterin, Part B

Specificaties
Gebonden, blz. | Engels
Elsevier Science | 2009
ISBN13: 9780123814296
Rubricering
Elsevier Science e druk, 2009 9780123814296
Onderdeel van serie Advances in Cancer Research
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Samenvatting

The biological function of clusterin (CLU, also known as ApoJ, SGP2, TRPM2, CLI) has been puzzling researchers since its discovery and characterization in the early 1980s. Approaches such as cloning, expression and functional characterization of the different protein products generated by the CLU gene have now produced a critical mass of information of tremendous biological importance that are teaching us an important lesson in molecular biology of gene expression regulation. This volume brings together the contributions of top researchers in the field, providing an overview and synthesis of the latest thought and findings relating to CLU.

Specificaties

ISBN13:9780123814296
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>1.    CLU and prostate cancer.</p> <p>S. Bettuzzi and F. Rizzi<br></p> <p>2.    The role of Clusterin (CLU) in malignant transformation and drug resistance in breast carcinomas </p> <p>Maximino Redondo; Teresa Tellez; María Jose Roldan.</p> <p>3.    CLU and COLON CANCER</p> <p>The dual face of CLU: from normal to malignant phenotype</p> <p>Mazzarelli P. Pucci S. Spagnoli L.G.</p> <p>4.    Clusterin (CLU) and lung cancer</p> <p>F. Panico*, <SUP>2</SUP>F. Rizzi*, <SUP>1</SUP>L.M. Fabbri, and <SUP>2</SUP>S. Bettuzzi°, <SUP>1</SUP>F. Luppi°</p><SUP> </SUP> <p>5.    CLUSTERIN AND CHEMORESISTANCE</p> <p>Julie Y. Djeu and Sheng Wei</p> <p>6.    CLU "in and out": looking for a link</p> <p>Pucci S.<SUP>1</SUP> , Mazzarelli P.<SUP> 1</SUP> , Nucci C.<SUP> 2</SUP>, Ricci F.<SUP> 2</SUP>, Spagnoli L.G.<SUP> 1</p></SUP> <p>7. Regulation of CLU gene expression by oncogenes and epigenetic<br>factors: Implications for tumorigenesis</p><SUP> <p></SUP>Arturo Sala,<SUP> 2 * </SUP>Saverio Bettuzzi, <SUP>3 </SUP>Sabina Pucci, <SUP>1 </SUP>Olesya Chayka, <SUP>4 </SUP>Michael Dews, and <SUP>4 </SUP>Andrei Thomas-Tikhonenko</p> <p>8. CONCLUSIONS AND PERSPECTIVES</p> <p>Saverio Bettuzzi</p>
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        Clusterin, Part B