Hsp90 in Cancer: Beyond the Usual Suspects
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
2016
ISBN13: 9780128022900
Rubricering
Onderdeel van serie
Advances in Cancer Research
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Hsp90 in Cancer: Beyond the Usual Suspects, the latest volume in the Advances in Cancer Research series, focuses on the multifunctional molecular chaperone Hsp90 which regulates the post-translational stability and function of a broad repertoire of client proteins and discusses some of the lesser-known aspects of how Hsp90 and its related family members enable oncogenic transformation and malignant progression.
Specificaties
Inhoudsopgave
1. Unusual Suspects in the Twilight Zone between the Hsp90 Interactome and Carcinogenesis<br>Evangelia Vartholomaiou, Pablo C. Echeverría and Didier Picard<br>2. Impact of Post-translational Modifications on the Anticancer Activity of Hsp90 Inhibitors<br>Mark R. Woodford, Diana Dunn, Jonelle B. Miller,Sami Jamal, Len Neckers and Mehdi Mollapour<br>3. Anticancer Inhibitors of Hsp90 Function: Beyond the Usual Suspects<br>Gaurav Garg, Anuj Khandelwal and Brian S. J. Blagg<br>4. HSP90 in Cancer: Transcriptional Roles in the Nucleus <br>S. K. Calderwood and L. Neckers<br>5. Hsp90 as a ‘Chaperone’ of the Epigenome: Insights and Opportunities for Cancer Therapy<br>Jennifer S. Isaacs<br>6. Emerging Roles of Extracellular Hsp90 in Cancer<br>Daniel Senh Wong and Daniel G. Jay<br>7. GRP94/gp96 in Cancer: Biology, Structure, Immunology and Drug Development <br>Bill X Wu, Feng Hong, Yongliang Zhang, Ephraim Ansa-Addo and Zihai Li<br>8. HSP90 and Immune Modulation in Cancer<br>Michael W. Graner<br>9. Hsp90: A Global Regulator of the Genotype-To-Phenotype Map in Cancers<br>Daniel Jarosz