Wen Xie
Elsevier Science
e druk, 2016
9780128029497
Drug Metabolism in Diseases
Specificaties
Gebonden, blz.
|
Engels
Elsevier Science |
2016
ISBN13: 9780128029497
Rubricering
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Drug Metabolism in Diseases is a comprehensive reference devoted to the current state of research on the impact of various disease states on drug metabolism. The book contains valuable insights into mechanistic effects and examples of how to accurately predict drug metabolism during these different pathophysiological states.
Each chapter clearly presents the effects of changes in drug metabolism and drug transporters on pharmacokinetics and disposition. This is a unique and useful approach for all those involved in drug discovery and development, and for clinicians and researchers in drug metabolism, pharmacology, and clinical pharmacology.
Specificaties
Inhoudsopgave
<p>1. Introduction of Drug Metabolism and Overview of Disease Effect on Drug Metabolism<br>2. Regulation of Drug-Metabolizing Enzymes and Drug Metabolism by Inflammatory Responses<br>3. Regulation of Drug Transporters by Inflammation<br>4. Drug Metabolism in Kidney Disease<br>5. Drug and Fatty Acid Cytochrome P450 Metabolism in Critical Care<br>6. Drug Metabolism in Cardiovascular Disease<br>7. Pharmacogenetic Factors That Affect Drug Metabolism and Efficacy in Type 2 Diabetes Mellitus<br>8. Hepatic Drug Metabolism in Pediatric Patients<br>9. Drug Metabolism in Pregnancy<br>10. Estrogen-Metabolizing Enzymes in Systemic and Local Liver Injuries: A Case Study of Disease–Drug Interaction<br>11. Xenobiotic Receptors in the Crosstalk Between Drug Metabolism and Energy Metabolism</p>