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Nuclear Architecture and Dynamics

Specificaties
Gebonden, blz. | Engels
Elsevier Science | 2017
ISBN13: 9780128034804
Rubricering
Elsevier Science e druk, 2017 9780128034804
Onderdeel van serie Translational Epigenetics
€ 193,00
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Samenvatting

Nuclear Architecture and Dynamics provides a definitive resource for (bio)physicists and molecular and cellular biologists whose research involves an understanding of the organization of the genome and the mechanisms of its proper reading, maintenance, and replication by the cell. This book brings together the biochemical and physical characteristics of genome organization, providing a relevant framework in which to interpret the control of gene expression and cell differentiation. It includes work from a group of international experts, including biologists, physicists, mathematicians, and bioinformaticians who have come together for a comprehensive presentation of the current developments in the nuclear dynamics and architecture field.

The book provides the uninitiated with an entry point to a highly dynamic, but complex issue, and the expert with an opportunity to have a fresh look at the viewpoints advocated by researchers from different disciplines.

Specificaties

ISBN13:9780128034804
Taal:Engels
Bindwijze:Gebonden

Inhoudsopgave

<p>PART I - CHROMATIN ORGANIZATION AND DYNAMICS<br>1. DNA mechanics<br>2. DNA supercoiling (omics)<br>3. Chromatin and chromosome folding (experiments)<br>4. Chromatin and chromosome folding (modeling)<br>5. Chromatin and chromosome physics<br>6. ncRNA in chromatin folding<br>7. Insulators <br>8. Condensins and cohesins<br>9. Long range interactions<br>10. Crowding</p> <p>PART II - NUCLEAR ENVELOPE, NUCLEAR BODIES AND NUCLEOCYTOPLASMIC TRAFFICKING<br>11. Nuclear bodies <br>12. Nucleolus <br>13. Transcription factories <br>14. Polycomb bodies<br>15. Nuclear lamina<br>16. Other components of the nucleoskeleton <br>17. Nuclear pores <br>18. Nuclear traffic</p> <p>PART III - MAIN NUCLEAR FUNCTIONS<br>19. Chromatin folding and DNA replication <br>20. Chromatin folding and DNA repair <br>21. Chromatin folding and transcription <br>22. Chromatin folding and recombination <br>23. Chromatin folding and differentiation <br>24. Nuclear mechanics and mechanotransduction <br>25. Altered nucleus and disease </p> <p>PART IV - SPECIFIC FEATURES OF NUCLEAR ORGANIZATION IN MAIN MODEL ORGANISMS<br>26. Yeast nucleus <br>27. Nematode nucleus <br>28. Drosophila nucleus <br>29. Plant nucleus <br>Conclusion and perspectives by the editors</p>
€ 193,00
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        Nuclear Architecture and Dynamics