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Ecology and Evolution of Cancer

Specificaties
Paperback, blz. | Engels
Elsevier Science | 2017
ISBN13: 9780128043103
Rubricering
Elsevier Science e druk, 2017 9780128043103
€ 92,14
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Ecology and Evolution of Cancer is a timely work outlining ideas that not only represent a substantial and original contribution to the fields of evolution, ecology, and cancer, but also goes beyond by connecting the interfaces of these disciplines. This work engages the expertise of a multidisciplinary research team to collate and review the latest knowledge and developments in this exciting research field.

The evolutionary perspective of cancer has gained significant international recognition and interest, which is fully understandable given that somatic cellular selection and evolution are elegant explanations for carcinogenesis. Cancer is now generally accepted to be an evolutionary and ecological process with complex interactions between tumor cells and their environment sharing many similarities with organismal evolution. As a critical contribution to this field of research the book is important and relevant for the applications of evolutionary biology to understand the origin of cancers, to control neoplastic progression, and to prevent therapeutic failures.

Specificaties

ISBN13:9780128043103
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>1. The Evolutionary Origins of Cancer and of Its Control by Immune Policing and Genetic Suppression<br>2. Cancer Prevalence and Etiology in Wild and Captive Animals<br>3. Infection and Cancer in Nature<br>4. Pseudohypoxia: Life at the Edge<br>5. The Genomic Landscape of Cancers<br>6. The Epigenetic Component in Cancer Evolution<br>7. Evolution of Cancer Defense Mechanisms Across Species<br>8. Coevolution of Tumor Cells and Their Microenvironment: “Niche Construction in Cancer”<br>9. Evolutionary Perspective of Tumorigenesis and Antitumor Immunity: A Comparative Approach<br>10. The Response of Cancer Cell Populations to Therapies<br>11. Ecology of the Metastatic Process<br>12. Transmissible Cancer: The Evolution of Interindividual Metastasis<br>13. Cancer in Animals: Reciprocal Feedbacks Between Evolution of Cancer Resistance and Ecosystem Functioning<br>14. Applying Tools From Evolutionary Biology to Cancer Research<br>15. Understanding Ancient Legacies to Expose and Exploit Cancer’s Evolutionary Vulnerabilities<br>16. Atavism Theory—An Introductory Discourse<br>17. Toward an Ultimate Explanation of Intratumor Heterogeneity<br>18. Obstacles to the Darwinian Framework of Somatic Cancer Evolution<br>19. Cancer as a Disease of Homeostasis: An Angiogenesis Perspective<br>20. Dormancy: An Evolutionary Key Phenomenon in Cancer Development<br>21. Controlling Rogue Cells in Cancer and Bacterial Infections<br>22. Searching for a Cancer-Proof Organism: It’s the Journey That Teaches You About the Destination<br>23. Ecology, Evolution, and the Cancer Patient</p>
€ 92,14
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        Ecology and Evolution of Cancer