<p>Section I Overview and Methods<br>1. Gene therapy methods and their applications in neurological disorders<br>2. Targeting transgene and RNA interference-based gene silencing sequences to astrocytes using viral vector-mediated approaches<br>3. Gene therapy using genomic DNA: Advances and challenges<br>4. Stem cell-based gene therapy in neurological disorders</p> <p>Section II Approaches to specific disorders<br>5. Targeting astrocytes with viral gene therapy for Alzheimer's disease<br>6. Prophylactic and therapeutic applications of catalytic immunoglobulin gene delivery in a mouse model of Alzheimer's disease<br>7. Lentiviral vector delivery of orexin gene to study potential role of orexin and sleep modulation in the pathogenesis of Alzheimer’s disease<br>8. Pharmacologically controlled neurotrophic factor gene therapy for Parkinson´s Disease<br>9. Gene therapy as a novel target for treatment of symptoms and medication complications in Parkinson’s disease<br>10. Inhibition of aggregation of mutant huntingtin by nucleic acid aptamers in vitro and in a yeast model of Huntington’s disease<br>11. Intraspinal delivery of recombinant AAV mediated Interleukin-10 modifies disease in ALS mice.<br>12. Differentiation of human induced pluripotent stem cells to Purkinje neurons<br>13. Expressing full-length dystrophin using adeno-associated virus<br>14. Genome editing therapy for Duchenne muscular dystrophy <br>15. AAV vector mediated gene delivery to neurons and glial cells in damaged spinal cord<br>16. Transplantation of human induced pluripotent stem cell-derived neural precursor cells for treatment of spinal cord injury<br>17. Viral transduction of primary Schwann cells using a Cre-lox system to regulate GDNF expression<br>18. Application of Herpes simplex virus vectors in treatment of neuropathic pain <br>19. Oncolytic virotherapy for gliomas: a preclinical and clinical summary</p>
