<p>I. EPIDEMIOLOGY AND OVERVIEW<br>1. Type 1 Diabetes Mellitus: An Overview<br>SALEH ADI AND ANDREA GERARD GONZALEZ<br>2. Prediabetes: Prevalence, Pathogenesis, and Recognition of Enhanced Risk<br>ALOK K. GUPTA, AJAY MENON, MEGHAN BRASHEAR AND WILLIAM D. JOHNSON<br>3. Targeting Prediabetes to Preempt Diabetes<br>SREEDHARAN N, MAHADEV RAO AND SONAL SEKHAR M<br>4. Obesity and Type 2 Diabetes in Youths: New Challenges to Overcome<br>NICOLA SANTORO, COSIMO GIANNINI AND SONIA CAPRIO<br>5. Roles of Environmental Pollution and Pesticides in Diabetes and Obesity: The Epidemiological Evidence<br>CHARLES J. EVERETT, DANIRA MEDUNJANIN AND IVAR L. FRITHSEN<br>6. An Overview of the Roles of the Gut Microbiome in Obesity and Diabetes<br>GILLIAN M. BARLOW, EUGENIA A. LIN AND RUCHI MATHUR</p> <p>II. TYPES OF DIABETES AND ITS CORRELATION WITH OTHER DISEASES<br>7. Role of Peripheral Neuropathy in the Development of Foot Ulceration and Impaired Wound Healing in Diabetes Mellitus<br>FRANCESCO TECILAZICH AND ARISTIDIS VEVES<br>8. The Association of Diabetes in the Onset of Dementia in the Elderly Population: An Overview<br>ABHAI KUMAR AND SMITA SINGH<br>9. The Role of Insulin Resistance in the Cardiorenal Syndrome<br>ADAM WHALEY-CONNELL AND JAMES R. SOWERS<br>10. An Overview on Diabetic Nephropathy<br>KEI FUKAMI AND SHO-ICHI YAMAGISHI<br>11. An Overview of Diabetic Retinopathy<br>SHINTARO NAKAO, SHIGEO YOSHIDA AND KOH-HEI SONODA<br>12. An Overview of Gestational Diabetes<br>CHRISTOPHER FEDERICO AND GABRIELLA PRIDJIAN<br>13. Diabetes, a Potential Threat to the Development and Progression of Tumor Cells in Individuals<br>SAYANTAN MAITRA, STABAK DAS AND PRADIPTA BANERJEE</p> <p>III. MOLECULAR INSIGHTS OF DIABETES AND METABOLIC SYNDROME<br>14. Lipid-Induced Insulin Resistance: Molecular Mechanisms and Clinical Implications<br>SATINATH MUKHOPADHYAY, DEEP DUTTA AND DIPYAMAN GANGULY<br>15. Gene–Environment Interaction in the Pathogenesis of Type 2 Diabetes<br>KIAN-PENG GOH<br>16. Renal Sodium-Glucose Transporter-2 Inhibitors and Antidiabetic Agents<br>ANAND S. NAIR, DEBASIS BAGCHI AND SREEJAYAN NAIR<br>17. Emerging Role of MicroRNA in Diabetes Mellitus<br>ANAND S. NAIR AND DEBASIS BAGCHI</p> <p>IV. PATHOPHYSIOLOGY<br>18. Insulin Resistance Syndrome: A Crucial Example Where a Physiological Continuum of Risks Needs Attention<br>HARRY G. PREUSS<br>19. Sleep Disturbances, Hypertension, and Type 2 Diabetes<br>MICHELLE A. MILLER AND FRANCESCO P. CAPPUCCIO<br>20. Roles of Pancreatic Cell Function, Liver, Skeletal Muscle, and Adipose Tissue in Diabetes and the Metabolic Syndrome<br>BEVERLY S. MÜHLHÄUSLER<br>21. Glycemic Variability and Its Clinical Implications<br>NARSINGH VERMA<br>22. Diabetic Wound Inflammation<br>SCOTT CHAFFEE, AMITAVA DAS, SUMAN SANTRA AND SASHWATI ROY<br>23. Sarcopenia, Diabetes, and Nutritional Intervention<br>SHEILA M. WICKS, IVAN SALAMON, ANGELA I. CALDERON, ESPERANZA CARCACHE DE BLANCO AND GAIL B. MAHADY</p> <p>V. PREVENTION AND TREATMENT 1: DIET, EXERCISE, SUPPLEMENTS AND ALTERNATIVE MEDICINES<br>24. Dietary Polyphenols, Gut Microbiota, and Intestinal Epithelial Health<br>MEIJUN ZHU<br>25. Reducing the Risk of Diabetes and Metabolic Syndrome With Exercise and Physical Activity<br>DAWN BLATT AND CHERI L. GOSTIC<br>26. Nutraceutical Impact on the Pathophysiology of Diabetes Mellitus<br>ODETE MENDES, LEE KOETZNER AND JAYSON CHEN<br>27. Therapeutic Effect of Fucoxanthin on Metabolic Syndrome and Type 2 Diabetes<br>KAZUO MIYASHITA, SHOW NISHIKAWA AND MASASHI HOSOKAWA<br>28. Safety and Antidiabetic Efficacy of a Novel Trigonella foenum-graecum Seed Extract<br>ANAND SWAROOP, MANASHI BAGCHI, HARRY G. PREUSS AND DEBASIS BAGCHI<br>29. Beneficial Effects of Chromium(III) and Vanadium Supplements in Diabetes<br>JOHN B. VINCENT<br>30. Protective Role of Alpha-Tocopherol in Diabetic Nephropathy<br>DAIKI HAYASHI AND YASUHITO SHIRAI<br>31. Antidiabetic Activity of Curcumin: Insight Into Its Mechanisms of Action<br>MARZENA WOJCIK, MICHAL KRAWCZYK AND LUCYNA A. WOZNIAK<br>32. Meal Plans for Diabetics: Caloric Intake, Calorie Counting, and Glycemic Index<br>PAULIN MOSZCZYŃSKI AND ZBIGNIEW TABAROWSKI</p> <p>VI. PREVENTION AND TREATMENT 2: DRUGS AND PHARMACEUTICALS<br>33. The Evolution of Glucose-Lowering Drugs for Type 2 Diabetes<br>ANDREW J. KRENTZ AND ALAN J. SINCLAIR<br>34. Current Antidiabetic Drugs: Review of Their Efficacy and Safety<br>MD. AKIL HOSSAIN AND ROKEYA PERVIN<br>35. HDACs in Diabetes: A New Era of Epigenetic Drug<br>LUÍS F. SCHÜTZ, MIN HI PARK AND MAHUA CHOUDHURY</p> <p>VII. NOVEL INNOVATIONS<br>36. Noninvasive Blood Glucose Measurement<br>YASUHIRO UWADAIRA AND AKIFUMI IKEHATA</p> <p>VIII. DIABETES IN ANIMALS AND TREATMENT<br>37. Diabetes Mellitus in Animals: Diagnosis and Treatment of Diabetes Mellitus in Dogs and CatsDEBORAH S. GRECO</p>
