Huile Gao,
Xiaoling Gao
Elsevier Science
e druk, 2018
9780128140017
Brain Targeted Drug Delivery Systems
A Focus on Nanotechnology and Nanoparticulates
Specificaties
Paperback, blz.
|
Engels
Elsevier Science |
2018
ISBN13: 9780128140017
Rubricering
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Brain Targeted Drug Delivery Systems: A Focus on Nanotechnology and Nanoparticulates provides a guide on nanoparticulates to both academic and industry researchers. The book discusses key points in the development of brain targeted drug delivery, summarizes available strategies, and considers the main problems and pitfalls evidenced in current studies on brain targeted drug delivery systems. As the brain is the most important organ in the human body, and disorders of the central nervous system (CNS) are the most serious threat to human life, this book highlights advances and new research in drug delivery methods to the brain.
Specificaties
Inhoudsopgave
<p>1. Introduction and overview</p> <p>Part I Physiology and principles for brain targeting drug delivery </p> <p>2. Anatomy and physiology of blood-brain barrier </p> <p>3. Recent progress in blood-brain barrier transportation research </p> <p>4. In vitro and in vivo models of BBB to evaluate brain targeting drug delivery </p> <p>Part II Nanoparticles-based brain targeting delivery strategies </p> <p>5. Receptor-mediated transportation through BBB </p> <p>6. Carrier-mediated transportation through BBB </p> <p>7. Brain drug delivery by adsorption-mediated transcytosis </p> <p>8. Efflux pump inhibition to enhance brain targeting delivery </p> <p>9. Physically open BBB </p> <p>10. Nanoparticle systems for nose-to-brain delivery </p> <p>11. Brain local delivery strategy </p> <p>Part III Nanoparticles-based brain targeting delivery for CNS disorder management </p> <p>12.Glioma targeted delivery systems </p> <p>13.Nanotherapeutic strategies for the treatment of neurodegenerative diseases </p> <p>14. Savaging brain ischemia by increasing brain uptake of neuroprotectants </p> <p>Part IV Perspective and pitfalls of nanoparticles-based brain targeting delivery</p> <p>15. Neurotoxicity concern about the brain targeting delivery systems </p> <p>16. The intra-brain distribution of brain targeting delivery systems </p> <p>17. The elimination of brain-targeted nanomaterials </p> <p>18. Perspective on brain targeting drug delivery systems </p>