Physiologically Based Pharmacokinetic (PBPK) Modeling

<p>Foreword<br>Melvin Andersen</p> <p>Preface<br>Jeffrey W. Fisher, Zhoumeng Lin and Jeffery M. Gearhart</p> <p>1. A history and recent efforts of selected physiologically based pharmacokinetic modeling topics<br>Zhoumeng Lin and Jeffrey W. Fisher</p> <p>2. Introduction to classical pharmacokinetics<br>Shruti V. Kabadi and Zhoumeng Lin</p> <p>3. Fundamentals of physiologically based pharmacokinetic modeling<br>Jeff Fisher, Xiaoxia Yang, Darshan Mehta, Conrad Housand and Zhoumeng Lin</p> <p>4. Physiologically based pharmacokinetic modeling software<br>C.E. Hack, A.Y. Efremenko, S.N. Pendse, C.A. Ellison, A. Najjar, N. Hewitt, A. Schepky and H.J. Clewell III</p> <p>5. Chemical absorption and writing code for portals of entry<br>Jeffrey W. Fisher, Jeffery M. Gearhart, Jerry L. Campbell Jr and Darshan Mehta</p> <p>6. Physiologically based pharmacokinetic model: distribution processes<br>Christopher Ruark</p> <p>7. Metabolism and physiologically based pharmacokinetic models<br>Jeffrey W. Fisher, Jerry L. Campbell Jr. and Zhoumeng Lin</p> <p>8. Physiologically based pharmacokinetic model: excretion via urine, feces, and breath<br>Sami Haddad and Andy Nong</p> <p>9. Sensitivity and Monte Carlo analysis techniques and their use in uncertainty, variability, and population analysis<br>Tammie R. Covington and Jeffery M. Gearhart</p> <p>10. Physiologically based pharmacokinetic model calibration, evaluation, and performance assessment<br>Zhoumeng Lin, Yi-Hsien Cheng, Wei-Chun Chou and Miao Li</p> <p>11. Examples of physiologically based pharmacokinetic modeling applied to risk assessment<br>Lisa M. Sweeney and Jeffery M. Gearhart</p> <p>12. Physiologically based pharmacokinetic models to support modernized chemical safety assessment<br>Miyoung Yoon</p>