Basics of Chimeric Antigen Receptor (CAR) Immunotherapy

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Paperback, blz. | Engels
Elsevier Science | 2019
ISBN13: 9780128195734
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Elsevier Science e druk, 2019 9780128195734
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Basics of Chimeric Antigen Receptor (CAR) Immunotherapy presents the latest on how T cell adoptive immunotherapy has progressed in its ultimate goal of curing metastatic malignant cancers. Recent clinical data obtained with checkpoint receptor blockade inhibitors and chimeric antigen receptor (CAR) therapy has been especially promising, thus generating renewed hope that we may be on the verge of finally curing cancer. Over the years, huge progress has been made in controlling several stage IV metastasized cancers through the clinical application of checkpoint receptor inhibitory drugs and CAR-Therapy that has seen unprecedented interest in the immunotherapy field.

Specificaties

ISBN13:9780128195734
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

1. An introduction to CAR immunotherapy2. Components and design of Chimeric Antigen Receptors (CARs)3. scFv cloning, vectors and CAR production in laboratory for preclinical application4. Production of CAR-T cells for clinical application5. Challenges and opportunities to improve CAR-TE cell therapy
€ 106,54
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        Basics of Chimeric Antigen Receptor (CAR) Immunotherapy