Proteolytic Signaling in Health and Disease

Specificaties
Paperback, blz. | Engels
Elsevier Science | 2021
ISBN13: 9780323856966
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Elsevier Science e druk, 2021 9780323856966
€ 185,80
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Samenvatting

In recent years, powered by evolving technologies and experimental design, studies have better illuminated the regulating role of proteolytic enzymes across human development and pathologies. Proteolytic Signaling in Health and Disease provides an in-depth discussion of fundamental physiological and developmental processes regulated by proteases, from protein turnover and autophagy to antigen processing and presentation and major histocompatibility complex (MHC) molecules. Moving on from basic biology, international chapter authors examine a range of pathological conditions associated with proteolysis, including inflammation, wound healing, and cancer. Later chapters discuss the newly discovered network of connected events among proteases (and their inhibitors), the so-called ‘protease web’, and how best to study it. This book also empowers new research with up-to-date analytical methods and step-by-step protocols for studying proteolytic signaling events.

Specificaties

ISBN13:9780323856966
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

<p>1. Proteolytic signalling: an introduction</p> <p>André Zelanis, Uilla Barcick and Maurício F. Camacho</p> <p>2. Ubiquitin-ligases: proteolytic signaling, protein turnover, and disease</p> <p>Felipe Roberti Teixeira, Patricia Passos, Camila Correia, Caio Almeida, Valentine Spagnol and Isabela Fernanda Morales Martins</p> <p>3. Lysosomal proteases and their role in signaling pathways</p> <p>Rebecca A.B. Burton, Samuel Bose and Thamali Ayagama</p> <p>4. Antigen processing and presentation through MHC molecules</p> <p>Niels Olsen Saraiva Câmara, Tamisa Honda and Barbara Padovani</p> <p>5. Proteolytic processing in autophagy</p> <p>João Agostinho Machado-Neto and Andrei Leitão</p> <p>6. Proteolysis in inflammatory diseases</p> <p>Antoine Dufour and Luiz de Almeida</p> <p>7. Proteolytic processing of laminin and the role of cryptides in tumoral biology</p> <p>Vanessa Morais Freitas, Ruy Gastaldoni Jaeger and Adriane Sousa de Siqueira</p> <p>8. Proteolytic signaling in wound healing</p> <p>Ulrich auf dem Keller, Konstantinos Kalogeropoulos and Louise Bundgaard</p> <p>9. Proteinases disbalance in oral cancer and other diseases </p> <p>Adriana Franco Paes Leme</p> <p>10. ‘Omics’ approaches for investigating protease degradomes in complex biological matrices</p> <p>Pitter F. Huesgen and Maithreyan Kuppusamy</p> <p>11. Protease web</p> <p>Nikolaus Fortelny and Wolfgang Esser-Skala</p> <p>12. The puzzle of proteolytic effects in hemorrhage induced by Viperidae snake venom metalloproteinases</p> <p>Milene Menezes, Dilza Trevisan-Silva, Daniela Cajado De Oliveira Souza Carvalho and Jessica de Alcantara Ferreira</p>
€ 185,80
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        Proteolytic Signaling in Health and Disease