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Nanosensors in Healthcare Diagnostics

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Paperback, blz. | Engels
Elsevier Science | 2024
ISBN13: 9780443191299
Rubricering
Elsevier Science e druk, 2024 9780443191299
Verwachte levertijd ongeveer 9 werkdagen

Samenvatting

Nanosensors in Healthcare Diagnostics examines the role of nanosensors in clinical microbiology, point-of-care sensing, clinical diagnostics, and therapy.

This book addresses the concept of nanosensors and their utilization in healthcare diagnostics, and therapy. It covers the principles and mechanisms involved in nanosensor-based diagnostics platforms. It also discusses various approaches and techniques used in the preparation of nanosensors as well as the biomedical application of nanosensors in clinical diagnostics and their significance in the detection, treatment, and management of diseases. This book is a useful reference for researchers, graduate students, and industry professionals studying nanosensors in biological and medical sciences.

Specificaties

ISBN13:9780443191299
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

List of contributors <br>About the editors<br>Foreword<br>Preface<br><br>CHAPTER 1 Nanobiosensors for point-of-care diagnostic applications<br>Namrata Sangwan, Radhika Dhawan, Arushi Chauhan, Jitender Singh and Pramod K. Avti<br><br>1.1 Introduction<br>1.2 Diagnostic biological markers <br>1.2.1 Protein biological markers<br>1.2.2 Metabolites biological markers<br>1.2.3 Nucleic acid biological markers<br>1.2.4 Pathogenic biological markers<br>1.3 Diagnostic role of nanobiosensors in biomedical field<br>1.3.1 Noncommunicable diseases<br>1.3.2 Communicable diseases<br>1.4 Summary and future perspective<br>References<br><br>CHAPTER 2 Gold-conjugated polymeric nanoparticles as biosensors<br>Sarin Palakkal<br><br>2.1 Introduction<br>2.1.1 Gold nanoparticle-based piezoelectric biosensors<br>2.2 Biosensor&rsquo;s state of the art<br>2.2.1 Gold nanoparticles sensing by fluorescence quenching<br>2.2.2 Gold nanoparticles surface plasmon resonance-based sensors<br>2.2.3 Detection of metal ions<br>2.3 Detection of small organic molecules and protein<br>2.4 Conclusions<br>References<br><br>CHAPTER 3 Biosensors for detection of Alzheimer&rsquo;s disease: a review<br>Manju Tewari<br>3.1 Introduction<br>3.1.1 Neurodegenerative diseases<br>3.1.2 Alzheimer&rsquo;s disease and its diagnosis<br>3.2 Biomarkers of Alzheimer&rsquo;s disease<br>3.2.1 Amyloid beta proteins<br>3.2.2 Tau protein<br>3.2.3 Apolipoprotein E4<br>3.3 Biosensors<br>3.3.1 Bioreceptors<br>3.3.2 Transducers<br>3.3.3 Signal amplification<br>3.4 Conclusion<br>Acknowledgments<br>Conflict of interest<br>References<br><br>CHAPTER 4 Nanodrug delivery—a noble approach in neurodegenerative disorder and glioblastoma<br>Kumudesh Mishra and Or Kakhlon<br><br>4.1 Introduction<br>4.2 Neurological diseases and treatment strategies<br>4.2.1 Neurodegenerative disease<br>4.3 The bloodbrain barrier and nanotechnology<br>4.4 Bloodbrain barrier crossing mechanism by nanomaterial<br>4.5 Nanocarriers in drug delivery<br>4.5.1 Inorganic nanocarriers for drug delivery<br>4.5.2 Organic nanocarriers<br>4.6 Recent advancements in nano-based treatment of brain disorders<br>4.6.1 Scaffold<br>4.6.2 Three- and four-dimensional printing<br>4.6.3 Induced pluripotent stem cells<br>4.6.4 Nanocarrier-based gene therapy<br>4.7 Clinical trials and current status of nanomedicines in the treatment of neurodegenerative diseases<br>4.8 Challenges and approaches to overcome barriers in the nano-based treatment of neurodegenerative diseases and glioblastoma multiforme<br>4.9 Conclusion and future perspective<br>References<br><br>CHAPTER 5 Advancements in nanosensors for an early detection of cancer<br>Ashmit Verma, Payal Kumar, Muzammil Kuddushi, Gayatri Joshi, Saumyakanti Khatua, Mukesh Dhanka and Deepak S. Chauhan<br><br>5.1 Introduction<br>5.2 Classification of nanosensors<br>5.2.1 Based on the materials used<br>5.2.2 Based on the mode of transduction<br>5.3 Role of nanosensors in an early detection of cancer<br>5.3.1 Detection of biomarkers<br>5.3.2 Detection of circulating tumor cells and exosomes<br>5.3.3 Probing of living cancer cells<br>5.3.4 Bioimaging of tumors<br>5.3.5 Artificial intelligence with nanosensors for bioimaging<br>5.3.6 Micro- and nanorobotics for an early detection of cancer<br>5.3.7 Conclusion<br>Acknowledgments<br>References<br><br>CHAPTER 6 Biomedical applications of nanobiosensors in cancer—recent advances and future prospects<br>Rajalakshmi Manikkam, Periyasamy Vijayalakshmi, Sabapathy Indu and Balakrishnan Solaimuthu<br><br>6.1 Introduction<br>6.1.1 Cancer onset and types<br>6.2 Cancer diagnostic tools<br>6.3 Nanotechnology<br>6.3.1 Classification of nanoparticles<br>6.3.2 Nanoparticles in biomedical applications<br>6.4 Nanomaterials as biosensors—a novel approach to cancer diagnostics<br>6.5 Cancer biomarkers<br>6.5.1 Detection method<br>6.6 Nanobiosensors<br>6.7 Clinical trial of biosensors<br>6.8 Advantages of nanobiosensors<br>6.9 Conclusion<br>References<br><br>CHAPTER 7 Nanomaterial-based nanosensors for food safety applications<br>Arushi Chauhan, Namrata Sangwan, Radhika Dhawan, Jitender Singh and Pramod K. Avti<br><br>7.1 Introduction<br>7.2 Food safety and nanosensors<br>7.3 Types of nanosensors<br>7.3.1 Optical sensors<br>7.3.2 Piezoelectric sensors<br>7.4 Application in healthcare trends<br>7.4.1 Food processing<br>7.4.2 Nutraceuticals delivery and food packaging<br>7.4.3 Food safety<br>7.5 Conclusion<br>References<br><br>CHAPTER 8 Nanosensors in medical microbiology<br>Muhammad Hashim Khan, Sohail Ahmad, Irum Batool Hashmi and Muhammad Badar<br><br>8.1 Introduction<br>8.1.1 Foodborne and clinical pathogens<br>8.2 Sensing of pathogens from food and clinical samples by using nanosensors<br>8.3 Types of nanobiosensors<br>8.3.1 Optical nanobiosensors<br>8.3.2 Colorimetric nanobiosensors<br>8.3.3 Electrochemical nanobiosensors<br>8.3.4 Thermometric nanobiosensors<br>8.3.5 Piezoelectric nanobiosensors<br>8.3.6 Microfluidic nanobiosensors<br>References<br><br>CHAPTER 9 Nanosensors technology for diagnosis of viral infections<br>Anupam Singh and Ashish Kumar Rai<br><br>9.1 Introduction<br>9.2 Nanosensors: a brief overview<br>9.2.1 Definition and functionality<br>9.2.2 Types of nanosensors<br>9.2.3 Nanosensors for viral detection<br>9.2.4 Nanosensors for specific viral infections<br>9.2.5 Challenges and limitations<br>9.2.6 Future perspectives<br>9.3 Conclusion<br>References<br><br>CHAPTER 10 Nanosensor-based therapeutic interventions to diagnose and cure bacterial infections<br>Shreya Mahato, Aparna Anand and Abhinay Sharma<br><br>10.1 Introduction<br>10.2 Conventional diagnostic and therapeutic methods of bacterial infections<br>10.3 Application of nanotechnology for bacterial infection management<br>10.4 Nanodiagnostics for bacterial infection<br>10.4.1 Magnetic nanoparticles<br>10.4.2 Metal nanoparticles<br>10.4.3 Nanowire-based biosensors<br>10.4.4 Quantum dots<br>10.4.5 Surface-enhanced photoluminescence<br>10.4.6 Surface-enhanced Raman scattering<br>10.4.7 Field-effect transistors<br>10.4.8 Fluorescent nanosensors<br>10.4.9 DNA microarray<br>10.5 Nanotherapeutics<br>10.5.1 Inorganic nanoparticles<br>10.5.2 Organic nanoparticles<br>10.5.3 Quantum dots<br>10.5.4 Nanowires<br>10.5.5 Nanocarriers<br>10.5.6 Others<br>10.6 Conclusion<br>References<br><br>CHAPTER 11 Use of nanotechnology in diagnosis and cure of mycotic infections<br>Shreya Mahato, Nupur Saxena, Aparna Anand and Abhinay Sharma<br><br>11.1 Introduction<br>11.2 Nanotechnology for diagnosis and cure of mycotic infections<br>11.3 Nanodiagnostic techniques<br>11.3.1 Gold nanoparticles<br>11.3.2 Magnetic nanoparticles<br>11.3.3 Quantum dots<br>11.3.4 Nanorods and nanotubes<br>11.3.5 Nanowires<br>11.3.6 Nanoprobes or nanosensors<br>11.3.7 Nanobarcodes<br>11.3.8 Surface-enhanced Raman scattering nanotags<br>11.3.9 Surface plasmon resonancebased detection<br>11.3.10 DNA microarray<br>11.3.11 Other techniques<br>11.4 Therapeutics of mycotic infections<br>11.4.1 Conventional therapeutic methods for fungal infections<br>11.4.2 Intervention of nanotechnology mycotic therapeutics<br>11.5 Conclusion<br>References<br><br>CHAPTER 12 Potential applications of nanotechnology in management of parasitic diseases<br>Aparna Anand and Abhinay Sharma<br><br>12.1 Introduction<br>12.2 Traditional diagnosis and treatment methods of parasitic diseases<br>12.3 Nanotechnology aided diagnosis and treatment of parasitic diseases<br>12.3.1 Liposomes<br>12.3.2 Solid lipid nanoparticles<br>12.3.3 Quantum dots<br>12.3.4 Polymeric nanoparticles<br>12.3.5 Metal nanoparticles<br>12.3.6 Nanosensors<br>12.3.7 Carbon nanotubes<br>12.3.8 Dendrimers<br>12.3.9 Nanoemulsions<br>12.3.10 Nanotechnology-based vaccines<br>12.4 Conclusion<br>References<br><br>CHAPTER 13 Green-synthesized nanoparticles for biomedical sensor technology<br>Ayse Baran, Mehmet Firat Baran, Polat Ipek, Aziz Eftekhari, Cumali Keskin, Mehmet Nuri Atalar and Mehmet Hakki Alma<br><br>13.1 Introduction<br>13.2 Obtaining of nanoparticles<br>13.2.1 Nanoparticle synthesis with plants or green synthesis<br>13.3 Biosensors<br>13.3.1 Classification of sensors<br>13.3.2 Introduction to nanobiosensors (nanomaterial-based biosensors)<br>13.3.3 Applications of nanobiosensors<br>13.4 Conclusion<br>References<br><br>Index

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        Nanosensors in Healthcare Diagnostics