Understanding the Pandemic

<p>Section 1: Coronaviruses (including SARS 1 and MERS), the Structure (sequence), Mechanism of Action<br>Introduction<br>1. Origin, Evolution and Spread of SARS-CoV-2<br>2. SARS-CoV-2 Spike Proteins in Infectivity <br>3. Structural and functional properties of the SARS-CoV-2 spike protein: potential vaccine and drug development for COVID-19<br>4. Population-Specific Polymorphisms and SARS-CoV-2 Infectivity<br>5. Insights into SARS-CoV-2 Structure: Approaches and Action of SARS-CoV-2 Main Protease Inhibitors<br>6. SARS-CoV-2, SARS-CoV, and MERS-COV: Similarities and Differences in Origin and Transmission<br><br>Section 2: Inflammation and Immune Response to SARS-CoV-2<br>Introduction<br>7. Characterization of the Immune Response with Viral Attack<br>8. Inflammation, Cytokines and COVID-19 Severity<br>9. Immunological Considerations for COVID-19: Vaccines and Other Protective Strategies<br>10. Virus-specific T cell response in SARS-CoV-2 infection and vaccinations<br>11. Oral and Gut Inflammation and Microbiota with COVID-19 <br>12. Implications of Inflammation: Bone and Joint Health with COVID-19<br>13. COVID-19 and immune dysfunction: Consequences, and natural remedies for management<br><br>Section 3: Pathological Findings with Clinical Correlation<br>Introduction<br>14. Pulmonary Pathology of Severe Covid-19<br>15. Histopathological Analysis of the Cardiovascular System in severe COVID-19<br>16. Postmortem Neuropathology in COVID-19<br>17. Renal Pathology in Severe Covid-19<br><br>Section 4: The Blood Vessels and COVID-19: Vascular Dysfunction and Coagulopathies<br>Introduction<br>18. Vascular Manifestations of COVID-19: Endothelial Dysfunction and Damage<br>19. Immunothrombosis involvement in COVID-19<br>20. COVID-19 associated coagulopathy<br>21. D-dimer in systemic circulation and COVID-19 outcome<br>22. Hypercoagulability in COVID-19<br><br>Section 5: Neuro-COVID-19 and its Long-Term Implications<br>Introduction<br>23. COVID and the Nervous System: Mechanisms and Consequences<br>24. Neuroinflammation: Unraveling Acute and Long COVID-19 Effects<br>25. Acute and Post-acute Neurologic and Psychiatric Manifestations in COVID-19<br>26. Pediatric Neurological and Neuropsychiatric Manifestations of COVID-19<br>27. Understanding the Pandemic: Pathophysiology, Transmission, and Treatment of Covid-19<br><br>Section 6: Should Covid-19 Concern Nephrologists? Why and to What Extent?"<br>Introduction<br>28. Acute Kidney Injury with COvid-19: Mechanisms, Management, and Long-term Outcomes<br>29. Models and Cellular Monolayers to Study the Effect of SARS-CoV-2 on Kidneys<br>30. Clinical implications of COVID-19 in chronic kidney disease and end-stage kidney disease<br><br>Section 7: Long COVID-19 (long term effects - summarizing of clinical reports in literature) <br>Introduction<br>31. Long COVID or Post-Acute Sequalae of COVID: An introduction<br>32. Long COVID: Pathophysiology and classification<br>33. Gender differences in Sequelae from COVID-19 Infection<br>34. Characterizing Long COVID-19: Lessons in the Clinic.<br>35. Implications of Long COVID for the Global Health Care System<br><br><br>Section 8: The Vaccines <br>Introduction<br>36. COVID-19: The Vaccine Development Strategies<br>37. mRNA vaccines: The New Frontier<br>38. Covid-19 vaccines: A Comprehensive review of Safety and Efficacy<br><br>Section 9: Handling the Spread: Public Health and Social Measures<br>Introduction<br>39. Lockdown measures during the COVID-19 pandemic<br>40. Efficacy of Facial masks against COVID-19<br>41. Vaccination Policies<br>42. Navigating the Impact of COVID-19 School Closures on Child Health, Education, and Society: A Call to Embrace Civil Discourse Across Identities, Sectors, and Disciplines<br>43. The Effect of the Pandemic on Care for Other Health Conditions<br>44. The role of smartphone-assisted tools for Covid-19 diagnostic, treatment, and quarantine<br><br>Section 10: From the Editors&rsquo; desk <br>45. What have we learnt from the COVID-19 pandemic?<br> </p>