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Antimicrobial Therapeutics and Drug Discovery

Specificaties
Paperback, blz. | Engels
Elsevier Science | 2026
ISBN13: 9780443365188
Rubricering
Elsevier Science e druk, 2026 9780443365188
Onderdeel van serie Drug Discovery Opinions
€ 196,59
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Samenvatting

Antimicrobial Therapeutics and Drug Discovery is a comprehensive resource that provides an overview of antimicrobial drug discovery. It covers a wide spectrum of pathogenic organisms causing human infections, exploring alternative therapeutic strategies beyond traditional small molecule drugs. The contents in the book are structured into four parts, each focusing on a different aspect of antimicrobial drug discovery. From exploring viral and host targets, understanding antibiotic resistance mechanisms, to the potential of nanomedicine and computational approaches, the book offers a comprehensive view of the field. Employing a multidisciplinary approach, chapters discuss the importance of drug discovery for fungi, Mycobacteria, Mycoplasma, and parasites, and offers insights into innovative biomedical approaches and combination therapies. By bridging the gap between experimental research and practical application, Antimicrobial Therapeutics and Drug Discovery is a key reference for pharmacologists and pharmaceutical scientists working in academic and corporate research. Medicinal chemists and microbiologists will also benefit from the multidisciplinary coverage of the book.

Specificaties

ISBN13:9780443365188
Taal:Engels
Bindwijze:Paperback

Inhoudsopgave

Part I: Antiviral Drug Discovery<br>1. Exploring Viral and Host Targets for Antiviral Drug Discovery<br>2. COVID-19 Challenges and its Therapeutics<br>3. From Lab to Clinic: The Evolution of Reverse Transcriptase Inhibitors in HIV Treatment<br>4. Targeting Hepatitis C Virus Polymerase: Non-Nucleoside Inhibitors (NNIs) and Drug Resistance<br>5. Challenges, Progress, and Prospects of Drug Discovery to Treat Chronic Hepatitis B (CHB) Infection<br>6. Discovery and Development of Antiviral Therapies for Influenza Virus Infections<br>7. Medicinal Chemistry Strategies for the Discovery and Development of Anti-Herpesvirus Drugs<br>8. Opportunities and Challenges in Targeted Protein Degradation for Antiviral Drug Discovery<br><br>Part II: Antibacterial Drug Discovery<br>9. Molecular Mechanisms of Antibiotic Resistance<br>10. Overview of the Antibiotics Approved in the Last Two Decades: Retrospect and Prospect<br>11. Antibiotic Resistance Breakers: Current Approaches and Future Directions<br>12. Innovative Approaches in Developing Antimicrobial Peptides for Drug-Resistant Bacterial Infections<br>13. The Potential of Antibody-Antibiotic Conjugates in Combatting Bacterial Diseases<br>14. Phage Therapy: Current Advancements and Future Prospects in Combating Antimicrobial Resistance<br><br>Part III: Drug Discovery for Miscellaneous Pathogens<br>15. Antifungal Drug Resistance: Current Mechanisms and Future Directions<br>16. Challenges, Unmet Clinical Needs, and Novel Approaches in the Discovery of Antifungal Drugs<br>17. Drug Discovery against Mycobacteria: The Success and Challenges<br>18. Future of Drug Development for the Treatment of Mycoplasma Infections<br>19. Antimalarial Drug Discovery: From Novel Molecules to Clinical Development<br><br>Part IV: Next-Generation Antimicrobial Strategies<br>20. Computational Approaches in Antimicrobial Drug Discovery<br>21. Multi-Omics Approaches for Antimicrobial Drug Discovery<br>22. Nanomedicine as a Next-Generation Antimicrobial Therapy: New Frontiers in Fighting Microbial Infections<br>23. Drug Repurposing: Innovative Antimicrobial Strategies to Combat Resistance<br>24. Drug Combinations: A Strategy to Extend the Life of Antimicrobials<br>25. Ethical Imperatives in Combating Antimicrobial Resistance: A Global Perspective
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        Antimicrobial Therapeutics and Drug Discovery