Part I. Introduction: 1. Normal development Mana Parast; Part II. Early Pregnancy Pathology: 2. Early pregnancy loss with normal karyotype Raymond W. Redline; 3. Early pregnancy loss with abnormal karyotype Raymond W. Redline; 4. Gestational trophoblastic disease Bradley J. Quade; Part III. Maternal Uteroplacental-Vascular Pathology: 5. Maternal vascular/trophoblastic developmental abnormalities Raymond W. Redline; 6. Distal villous hypoplasia, focal and diffuse Brendan Fitzgerald and Sarah Keating; 7. Maternal vascular malperfusion Raymond W. Redline; 8. Loss of maternal vascular integrity Drucilla J. Roberts; Part IV. Fetal Stromal-Vascular Pathology: 9. Fetal-stromal vascular developmental abnormalities Raymond W. Redline; 10. Fetal vascular malperfusion Theonia K. Boyd; 11. Loss of fetal vascular integrity Drucilla J. Roberts; Part V. Inflammatory Processes: 12. Placental infections Drucilla J. Roberts; 13. Chronic villitis/ villitis of unknown etiology (Vue) Mana Parast; 14. Chronic inflammatory lesions sometimes associated with villitis of unknown etiology (Vue) Suzanne M. Jacques and Faisal Qureshi; 15. Chronic histiocytic intervillositis Raymond W. Redline; Part VI. Other Pathologic Processes: 16. Placental size, shape, and umbilical cord abnormalities Raymond W. Redline; 17. Perivillous fibrin deposition Drucilla J. Roberts; 18. Atypical intraplacental hemorrhages/ thrombi Brendan Fitzgerald and Sarah Keating; 19. Meconium effects Theonia K. Boyd; 20. Increased circulating fetal nucleated red blood cells Theonia K. Boyd; 21. Early and late membrane/amnion rupture and amnion nodosum Suzanne M. Jacques and Faisal Qureshi; 22. Metastatic tumors Drucilla J. Roberts; 23. Heterotopias and germ cell tumors Suzanne M. Jacques and Faisal Qureshi; 24. Lysosomal storage disease, Bartter syndrome, and mimics Raymond W. Redline; Part VII. Pathology of Multiple Gestations: 25. The pathology of monochorionic placentation Monique E. De Paepe; 26. Dichorionic or higher order multiple gestations Monique E. De Paepe; Part VIII. Uteroplacental Pathology: 27. Abnormal placental location Kelly Devereaux and Ann Folkins; 28. Morbidly adherent placenta Linda M. Ernst; 29. Uterine rupture/ dehiscence Sydney Card and Ann Folkins; 30. Postpartum hemorrhage Koah Vierkoetter and Ann Folkins; Part IX. Clinicopathologic Correlations: Placental Pathology and Adverse Pregnancy Outcomes: 31. Spontaneous preterm delivery (premature labor, premature rupture of membranes, vaginal bleeding, cervical insufficiency) Raymond W. Redline; 32. Fetal growth restriction Ann Folkins; 33. Fetal death Theonia K. Boyd; 34. Central nervous system injury Raymond W. Redline; 35. Recurrent pregnancy loss Raymond W. Redline.