Wen-Quan Zou,
Pierluigi Gambetti
Springer New York
2013e druk, 2012
9781461453048
Prions and Diseases
Volume 1, Physiology and Pathophysiology
Specificaties
Gebonden, 241 blz.
|
Engels
Springer New York |
2013e druk, 2012
ISBN13: 9781461453048
Rubricering
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Volume I highlights the association of the cellular prion protein (PrPC) with copper and zinc, the potential roles of PrPC in Alzheimer’s disease and cancers, insoluble PrPC, PMCA, molecular and cellular mechanisms of PrPSc formation and clearance, possible co-factors involved in the conversion of PrPC into PrPSc, infectious and pathogenic forms of PrP, cell biology of prions, prion strains and their interference, as well as yeast prions and their inheritable and structural traits. This unique volume will take you through the fascinating chronicle of prions in mammals, yeast, and fungi.
Specificaties
ISBN13:9781461453048
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:241
Uitgever:Springer New York
Druk:2013
Inhoudsopgave
<p>Chapter 1 Transmissible Spongiform Encephalopathy: from the High Middle Ages to Daniel Carlton Gajdusek<br>Paul Brown</p><p>Chapter 2 The Rich Chemistry of the Copper and Zinc Sites in Cellular Prion Protein<br>Glenn L. Millhauser</p><p>Chapter 3 Role of Cellular Prion Protein in the Amyloid-ß Oligomer Pathophysiology of Alzheimer’s Disease<br>Adam C. Kaufman, Stephen M. Strittmatter</p><p>Chapter 4 Cellular Prion Protein and Cancers<br>Wei Xin, Man-sun Sy, Chaoyang Li</p><p>Chapter 5 Insoluble Cellular Prion Protein<br>Wen-Quan Zou</p><p>Chapter 6 Protein Misfolding Cyclic Amplification<br>Fabio Moda, Sandra Pritzkow, Claudio Soto</p><p>Chapter 7 Cofactor Involvement in Prion Propagation<br>Surachai Supattapone, Michael B. Miller</p><p>Chapter 8 Prion Protein Conversion and Lipids<br>Jiyan Ma</p><p>Chapter 9 New Perspectives on Prion Conversion: Introducing a Mechanism of Deformed Templating<br>Ilia V. Baskakov</p><p>Chapter 10 Infectious and Pathogenic Forms of Prion Protein<br>Emiliano Biasini, David A. Harris</p><p>Chapter 11 Cellular Mechanisms of Propagation and Clearance<br>Hermann M. Schatzl</p><p>Chapter 12 Molecular Mechanisms Encoding Quantitative and Qualitative Traits of Prion Strains<br>Jiri G. Safar</p><p>Chapter 13 Modeling the Cell Biology of Prions<br>Richard Rubenstein, Robert B. Petersen</p><p>Chapter 14 Prion Strain Interference <br>Charles R. Schutt, Ronald A. Shikiya, Jason C. Bartz<br> <br>Chapter 15 Introduction to Yeast and Fungal Prions<br>Reed B. Wickner</p><p>Chapter 16 Yeast Prions are Pathogenic, in-register Parallel Amyloids<br>Reed B. Wickner, Herman K. Edskes, David A. Bateman, Amy C. Kelly, Anton Gorkovskiy</p>