Metastatic Bone Disease
Fundamental and Clinical Aspects
Samenvatting
"Metastatic Bone Disease: Fundamental and Clinical Aspects"
is an expanded version of a workshop on bone metastases
which was held in Heidelberg, Germany, in April 1993. Bone
metastases very often develop from malignant tumors and lead
to complications which considerably diminish the quality of
life of the patient. Bone pain, pathological fractures, and
hypercalcemic syndrome should be recognized and treated ear-
ly, so as to prevent any further morbidity and immobilizati-
on. Antiosteolytic substances such as biophosphonate can
supplement the established palliative and supportive thera-
pies.
Highly qualified basic researchers and clinicians in
pathophysiology, diagnosis, and treatment of metastatic bone
disease have contributed to this book, providing a good
overview ofpresent knowledge and research. The book will be
of interest not only to specialists, but also to any physi-
cian interested in oncology.