Branch D. Moody
Springer Berlin Heidelberg
2007e druk, 2007
9783540695103
T Cell Activation by CD1 and Lipid Antigens
Specificaties
Gebonden, 348 blz.
|
Engels
Springer Berlin Heidelberg |
2007e druk, 2007
ISBN13: 9783540695103
Rubricering
Onderdeel van serie
Current Topics in Microbiology and Immunology
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
There is increasing evidence that the CD1 system has been conserved throughout mammalian evolution and is capable of presenting structurally diverse diacyglycerol, sphingolipid, polyisoprenol and lipopeptide antigens. This volume provides a comprehensive discussion of these basic aspects of CD1 biology and summarizes the most recent research into the role of CD1 in infectious, autoimmune, allergic and neoplastic disease.
Specificaties
ISBN13:9783540695103
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:348
Uitgever:Springer Berlin Heidelberg
Druk:2007
Inhoudsopgave
Section 1 - Molecular Biology.- Chapter 1 - Evolutionary Biology of the CD1.- Chapter 2 - Architecture of CD1 Proteins.- Chapter 3 - Structures and Biology of Self Lipid Antigens.- Chapter 4 - Structures and Functions of Microbial Lipid Antigens.- Section 2 - Cellular Biology.- Chapter 5 - CD1 Expression on Antigen Presenting Cells.- Chapter 6 - Pathways of CD1 and Lipid Antigen Delivery, Trafficking, Processing, Loading and Presentation.- Chapter 7 - TCR-Mediated Recognition of Glycolipid CD1 Complexes.- Chapter 8 - Development and Selection of Va14i NKT Cells.- Section 3 - Disease.- Chapter 9 - CD1-Restricted T Cells in Host Defense to Infectious Diseases.- Chapter 10 - NKT Cells and Autoimmune Diseases: Unraveling the Complexity.- Chapter 11 - iNKT Cells in Allergic Disease.- Chapter 12 - CD1-Restricted T Cells and Tumor Immunity.- Chapter 13 - Harnessing NKT Cells for Therapeutic Applications.- Subject index