Drug Discovery and Evaluation: Safety and Pharmacokinetic Assays

<p>Safety Pharmacokinetics</p><p>Absorption / in vitro Tests / Cell Based</p><p></p><p>Absorption / in vitro Tests / Non Cell Based</p><p>Absorption / in vivo Tests (Radiolabeled)</p><p>Bioanalytical Assays - RIA/EIA</p><p>Bioanalytical Assays / Gas Chromatography (GC)</p><p>Bioanalytical Assays / LC-MS/MS</p><p>Bioanalytical Assays / Toxicokinetics</p><p>Clinical Studies / Typical Designs</p><p>Distribution - Across Barriers</p><p>Distribution - in vivo - Perfused Organs</p><p>Distribution / in vitro Tests / Protein Binding</p><p>Distribution / in vivo / Other Methods</p><p>Distribution in vivo</p><p>Drug-drug Interaction / Enzyme Induction</p><p>Drug-drug Interaction / Enzyme Inhibition</p><p>In silico ADME Modeling</p><p>Metabolism Studies in vitro and in vivo</p><p>Pharmacogenomics in DME</p><p>Physicochemical Properties</p><p>Population Pharmacokinetics</p><p>Safety Pharmacokinetics: Introduction</p><p>Typical PK/PD Approaches in Preclinical and Clinical Development</p><p> </p><p>Safety Pharmacology</p><p>Analgesic Activity and Intravenous and Inhalation Anesthetics</p><p>Anti-inflammatory and Antiarthrotic Activity</p><p>Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic acids, and Mammalian cells</p><p>Blood Constituents</p><p>Cardiovascular Pharmacology</p><p>Central Nervous System</p><p>Chronobiology and the Implications for Safety Pharmacology</p><p>Cochlear Safety Tests</p><p>Drug Safety on Herbal Medical Products</p><p>Drug-Addiction and Drug-Dependency</p><p>Endocrine Pharmacology</p><p>Magnetic Resonance Imaging and Imaging in Pharmaceutical Safety Assessment</p><p>Metabolism Pharmacology</p><p>Ocular Safety Tests</p><p>Oncology Pharmacology</p><p>Peripheral Nervous System</p><p>Pulmonary Pharmacology</p><p>Renal System</p><p>Safe Chemicals / REACH</p><p>Safety Pharmacology in Biologics, Antibiotics and Monoclonics</p><p>Safety Pharmacology: Introduction and Guidelines</p><p>Sensory Systems</p><p>Skin Pharmacology</p><p>Stem Cells in Safety Pharmacology</p><p>Study design and statistics</p><p>Transgenic Animals</p><p>Zebrafish Model</p><p> </p><p>Safety Toxicology</p><p>Genotoxicity</p><p>In silico Methods</p><p>In vitro toxicity testing</p><p>International Guidelines</p><p>OMICS Technologies</p><p>Reproductive Toxicology</p><p>Safety Toxicology: Introduction</p><p>Testing of Medical Devices</p><p>Testing of Monoclonal Antibodies</p><p>Toxicogenomics</p><p></p><p></p><p>Absorption / in vitro Tests / Non Cell Based</p><p>Absorption / in vivo Tests (Radiolabeled)</p><p>Bioanalytical Assays - RIA/EIA</p><p>Bioanalytical Assays / Gas Chromatography (GC)</p><p>Bioanalytical Assays / LC-MS/MS</p><p>Bioanalytical Assays / Toxicokinetics</p><p>Clinical Studies / Typical Designs</p><p>Distribution - Across Barriers</p><p>Distribution - in vivo - Perfused Organs</p><p>Distribution / in vitro Tests / Protein Binding</p><p>Distribution / in vivo / Other Methods</p><p>Distribution in vivo</p><p>Drug-drug Interaction / Enzyme Induction</p><p>Drug-drug Interaction / Enzyme Inhibition</p><p>In silico ADME Modeling</p><p>Metabolism Studies in vitro and in vivo</p><p>Pharmacogenomics in DME</p><p>Physicochemical Properties</p><p>Population Pharmacokinetics</p><p>Safety Pharmacokinetics: Introduction</p><p>Typical PK/PD Approaches in Preclinical and Clinical Development</p><p> </p><p>Safety Pharmacology</p><p>Analgesic Activity and Intravenous and Inhalation Anesthetics</p><p>Anti-inflammatory and Antiarthrotic Activity</p><p>Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic acids, and Mammalian cells</p><p>Blood Constituents</p><p>Cardiovascular Pharmacology</p><p>Central Nervous System</p><p>Chronobiology and the Implications for Safety Pharmacology</p><p>Cochlear Safety Tests</p><p>Drug Safety on Herbal Medical Products</p><p>Drug-Addiction and Drug-Dependency</p><p>Endocrine Pharmacology</p><p>Magnetic Resonance Imaging and Imaging in Pharmaceutical Safety Assessment</p><p>Metabolism Pharmacology</p><p>Ocular Safety Tests</p><p>Oncology Pharmacology</p><p>Peripheral Nervous System</p><p>Pulmonary Pharmacology</p><p>Renal System</p><p>Safe Chemicals / REACH</p><p>Safety Pharmacology in Biologics, Antibiotics and Monoclonics</p><p>Safety Pharmacology: Introduction and Guidelines</p><p>Sensory Systems</p><p>Skin Pharmacology</p><p>Stem Cells in Safety Pharmacology</p><p>Study design and statistics</p><p>Transgenic Animals</p><p>Zebrafish Model</p><p> </p><p>Safety Toxicology</p><p>Genotoxicity</p><p>In silico Methods</p><p>In vitro toxicity testing</p><p>International Guidelines</p><p>OMICS Technologies</p><p>Reproductive Toxicology</p><p>Safety Toxicology: Introduction</p><p>Testing of Medical Devices</p><p>Testing of Monoclonal Antibodies</p><p>Toxicogenomics</p><p></p><p></p><p>Biomaterials in Their Role in Creating New Approaches for the Delivery of Drugs, Proteins, Nucleic acids, and Mammalian cells</p><p>Blood Constituents</p><p>Cardiovascular Pharmacology</p><p>Central Nervous System</p><p>Chronobiology and the Implications for Safety Pharmacology</p><p>Cochlear Safety Tests</p><p>Drug Safety on Herbal Medical Products</p><p>Drug-Addiction and Drug-Dependency</p><p>Endocrine Pharmacology</p><p>Magnetic Resonance Imaging and Imaging in Pharmaceutical Safety Assessment</p><p>Metabolism Pharmacology</p><p>Ocular Safety Tests</p><p>Oncology Pharmacology</p><p>Peripheral Nervous System</p><p>Pulmonary Pharmacology</p><p>Renal System</p><p>Safe Chemicals / REACH</p><p>Safety Pharmacology in Biologics, Antibiotics and Monoclonics</p><p>Safety Pharmacology: Introduction and Guidelines</p><p>Sensory Systems</p><p>Skin Pharmacology</p><p>Stem Cells in Safety Pharmacology</p><p>Study design and statistics</p><p>Transgenic Animals</p><p>Zebrafish Model</p><p> </p><p>Safety Toxicology</p><p>Genotoxicity</p><p>In silico Methods</p><p>In vitro toxicity testing</p><p>International Guidelines</p><p>OMICS Technologies</p><p>Reproductive Toxicology</p><p>Safety Toxicology: Introduction</p><p>Testing of Medical Devices</p><p>Testing of Monoclonal Antibodies</p><p>Toxicogenomics</p><p></p><p></p>