Hubert Hilbi
Springer Berlin Heidelberg
2014e druk, 2013
9783642405907
Molecular Mechanisms in Legionella Pathogenesis
Specificaties
Gebonden, 295 blz.
|
Engels
Springer Berlin Heidelberg |
2014e druk, 2013
ISBN13: 9783642405907
Rubricering
Onderdeel van serie
Current Topics in Microbiology and Immunology
Levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
Legionnaires’ disease, a potentially fatal type of pneumonia primarily affecting elderly and immuno-compromised persons, is caused by the ubiquitous environmental bacterium Legionella pneumophila. This book offers authoritative reviews of different facets of its virulence, focusing on comparative phagocyte infection, virulence gene regulation, biochemical functions of effector proteins and cellular pathogen-host interactions, as well as host responses and immunity to L. pneumophila. Taken together, the contributions in this compilation provide a state-of-the-art overview of current insights into the molecular pathogenesis of the opportunistic and potentially fatal pathogen L. pneumophila.
Specificaties
ISBN13:9783642405907
Taal:Engels
Bindwijze:gebonden
Aantal pagina's:295
Uitgever:Springer Berlin Heidelberg
Druk:2014
Inhoudsopgave
<p>From amoeba to macrophages: exploring the molecular mechanisms of Legionella infection in both hosts</p><p>Pedro Escoll, Monica Rolando, Laura Gomez-Valero and Carmen Buchrieser</p><p>The Legionella pneumophila two-component regulatory systems that participate in the regulation of Icm/Dot effectors</p><p>Gil Segal</p><p>Facets of small RNA-mediated regulation in Legionella pneumophila</p><p>Hana Trigui, Nilmini Mendis, Laam Li, Mariam Saad and Sebastien P. Faucher</p><p>Type II secretion and Legionella virulence</p><p>Nicholas P. Cianciotto</p><p>Effector translocation by the Legionella Icm/Dot type IV secretion system</p><p>Jiazhang Qiu and Zhao-Qing Luo</p><p>Modulation of small GTPases by Legionella</p><p>Roger S. Goody and Aymelt Itzen</p><p>Host lipidation: A mechanism for spatial regulation of Legionella effectors</p><p>Stanimir S. Ivanov and Craig Roy</p><p>Phosphoinositides and the Legionella pathogen vacuole</p><p>Ina Haneburger and Hubert Hilbi</p><p>Legionella phospholipases implicated in virulence</p><p>Katja Kuhle and Antje Flieger</p><p>Cytotoxic glucosyltransferases of Legionella pneumophila</p><p>Yury Belyi, Thomas Jank and Klaus Aktories</p><p>Modulation of the ubiquitination machinery by Legionella</p><p>Andree Hubber, Tomoko Kubori and Hiroki Nagai</p><p>Host signal transduction and protein kinases implicated in Legionella infection</p><p>Andrew D. Hempstead and Ralph R. Isberg</p><p>Mouse models of Legionnaires´ disease</p><p>Andrew S Brown, Ian R van Driel and Elizabeth L Hartland</p>