B.J.A. Furr
Birkhäuser Basel
2e druk, 2007
9783764386924
Aromatase Inhibitors
Specificaties
Paperback, 189 blz.
|
Engels
Birkhäuser Basel |
2e druk, 2007
ISBN13: 9783764386924
Rubricering
Onderdeel van serie
Milestones in Drug Therapy
Verwachte levertijd ongeveer 9 werkdagen
Gratis verzonden
Samenvatting
This book provides the first comprehensive overview on the different aromatase inhibitors. Whereas the first aromatase inhibitors to be used therapeutically could be shown to produce drug-induced inhibition of the enzyme and therapeutic benefits in patients with breast cancer, they were not very potent and lacked specificity. However, second-generation drugs were developed and most recently third-generation inhibitors have evolved which possess remarkable specificity and potency.
Specificaties
ISBN13:9783764386924
Taal:Engels
Bindwijze:paperback
Aantal pagina's:189
Uitgever:Birkhäuser Basel
Druk:2
Inhoudsopgave
<P>Background and development of aromatase inhibitors.- Aromatase inhibitors and models for breast cancer.- Clinical pharmacology of aromatase inhibitors.- Clinical studies with exemestane.- Clinical studies with letrozole.- Clinical studies with anastrozole.- The third-generation aromatase inhibitors: a clinical overview.- Lessons from the ArKO mouse.- Possible additional therapeutic uses of aromatase inhibitors</P>